β-Ketothioester as a reactive Knoevenagel donor

Yujiro Hayashi; Yuji Miyamoto; Mitsuru Shoji

doi:10.1016/S0040-4039(02)00675-5

β-Ketothioester as a reactive Knoevenagel donor

Yujiro Hayashi, Yuji Miyamoto, Mitsuru Shoji

Research output: Contribution to journal › Article › peer-review

12 Citations (Scopus)

Abstract

The Knoevenagel condensation of β-ketothioesters with various aldehydes proceeds efficiently, affording the condensation products in moderate to good yield even in cases where the reactions of the corresponding β-ketoesters give the adducts in only low to moderate yield.

Original language	English
Pages (from-to)	4079-4082
Number of pages	4
Journal	Tetrahedron Letters
Volume	43
Issue number	22
DOIs	https://doi.org/10.1016/S0040-4039(02)00675-5
Publication status	Published - 2002 May 27
Externally published	Yes

Keywords

Knoevenagel reaction
β-ketoester
β-ketothioester

ASJC Scopus subject areas

Biochemistry
Drug Discovery
Organic Chemistry

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10.1016/S0040-4039(02)00675-5

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title = "β-Ketothioester as a reactive Knoevenagel donor",

abstract = "The Knoevenagel condensation of β-ketothioesters with various aldehydes proceeds efficiently, affording the condensation products in moderate to good yield even in cases where the reactions of the corresponding β-ketoesters give the adducts in only low to moderate yield.",

keywords = "Knoevenagel reaction, β-ketoester, β-ketothioester",

author = "Yujiro Hayashi and Yuji Miyamoto and Mitsuru Shoji",

note = "Funding Information: This research was supported by the Sumitomo Foundation and a Grant-in-Aid for Scientific Research from the Ministry of Education, Culture, Sports, Science and Technology, Japan.",

year = "2002",

month = may,

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doi = "10.1016/S0040-4039(02)00675-5",

language = "English",

volume = "43",

pages = "4079--4082",

journal = "Tetrahedron Letters",

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number = "22",

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TY - JOUR

T1 - β-Ketothioester as a reactive Knoevenagel donor

AU - Hayashi, Yujiro

AU - Miyamoto, Yuji

AU - Shoji, Mitsuru

N1 - Funding Information: This research was supported by the Sumitomo Foundation and a Grant-in-Aid for Scientific Research from the Ministry of Education, Culture, Sports, Science and Technology, Japan.

PY - 2002/5/27

Y1 - 2002/5/27

N2 - The Knoevenagel condensation of β-ketothioesters with various aldehydes proceeds efficiently, affording the condensation products in moderate to good yield even in cases where the reactions of the corresponding β-ketoesters give the adducts in only low to moderate yield.

AB - The Knoevenagel condensation of β-ketothioesters with various aldehydes proceeds efficiently, affording the condensation products in moderate to good yield even in cases where the reactions of the corresponding β-ketoesters give the adducts in only low to moderate yield.

KW - Knoevenagel reaction

KW - β-ketoester

KW - β-ketothioester

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U2 - 10.1016/S0040-4039(02)00675-5

DO - 10.1016/S0040-4039(02)00675-5

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VL - 43

SP - 4079

EP - 4082

JO - Tetrahedron Letters

JF - Tetrahedron Letters

IS - 22

ER -

β-Ketothioester as a reactive Knoevenagel donor

Abstract

Keywords

ASJC Scopus subject areas

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