15-year outcomes of the JOCRI study (JOCRIED study): a randomised comparison of off-pump and on-pump multiple arterial coronary revascularisation

Naoki Tadokoro, Satsuki Fukushima, Kimito Minami, Yusuke Shimahara, Naonori Kawamoto, Takashi Kakuta, Satoshi Numata, Hitoshi Yaku, Hirofumi Takemura, Kenji Iino, Masami Ochi, Yosuke Ishii, Hideichi Wada, Noritoshi Minematsu, Hideyuki Shimizu, Junjiro Kobayashi, Tomoyuki Fujita

Research output: Contribution to journalArticlepeer-review

1 Citation (Scopus)


Objective: The Japanese Off-Pump Coronary Revascularization Investigation (JOCRI) study reported a non-significant difference in early outcomes and graft patency between off-pump coronary artery bypass grafting and on-pump coronary artery bypass grafting in 2005. The JOCRIED study aimed to review the long-term outcomes of the JOCRI study participants. Method and results: The JOCRIED study enrolled 123 of the JOCRI study participants completing the clinical follow-up between August 2018 and August 2020; 61 patients in the off-pump group and 62 patients in the on-pump group. The follow-up period was 13.8 ± 2.8 years. The groups were compared regarding mortality, the incidence of major adverse cardiac and cerebrovascular events and repeat revascularisation. The 15-year cumulative survival rate (off-pump vs on-pump, respectively; 77.7% vs 75.3%; p = 0.85), major adverse events-free survival rate (62.5% vs 55.6%; p = 0.27) and repeat revascularisation-free rate (84.8% vs 78.0%; p = 0.16) were not significantly different between the two groups. Revascularisation was the most common major adverse events in the JOCRIED participants. Although percutaneous coronary intervention was performed in 8 patients (13%) in the off-pump group and in 14 patients (23%) in the on-pump group (p = 0.23), no patients underwent redo coronary artery bypass grafting. Conclusions: Off-pump coronary artery bypass grafting provides comparable 15-year outcomes to on-pump coronary artery bypass grafting.

Original languageEnglish
Pages (from-to)151-157
Number of pages7
JournalGeneral thoracic and cardiovascular surgery
Issue number3
Publication statusPublished - 2023 Mar


  • Coronary artery bypass grafting
  • Multiple arterial conduits
  • Off-pump

ASJC Scopus subject areas

  • Surgery
  • Pulmonary and Respiratory Medicine
  • Cardiology and Cardiovascular Medicine


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