2.8 Chiral Pool Synthesis: Chiral Pool Syntheses Starting from Carbohydrates

N. Chida, T. Sato

Research output: Chapter in Book/Report/Conference proceedingChapter

16 Citations (Scopus)


Chiral pool synthesis is one of the most effective methods for the preparation of optically active compounds. This chapter focuses on the synthesis of biologically active natural products based on the chiral pool approach starting from carbohydrates. Reports on the synthesis of structurally complex molecules, that is, macrocyclic (oleandomycin and okadaic acid), polycyclic (brevetoxin B), heterocyclic (thienamycin and salinosporamide A), and carbocyclic (verrucarol, calystegine B2, tetrodotoxin, cyclophellitol, and morphine) compounds by way of the regio- and stereoselective transformations of readily available monosaccharides would be reviewed.

Original languageEnglish
Title of host publicationSynthetic Methods I - Chiral Pool and Diastereoselective Methods
PublisherElsevier Ltd
Number of pages33
ISBN (Print)9780080951683
Publication statusPublished - 2012 Sept


  • Brevetoxin B
  • Cyclophellitol
  • Morphine
  • Okadaic acid
  • Oleandomycin
  • Salinosporamide A
  • Tetrodotoxin
  • Thienamycin
  • Verrucarol

ASJC Scopus subject areas

  • Chemistry(all)


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