3D Visualization of Skin Inner Tissue from Confocal Microscopic Images

J. Wang, H. Saito, S. Ozawa, T. Kuwahara, T. Yamashita, M. Takahashi

Research output: Contribution to journalConference articlepeer-review

1 Citation (Scopus)


Analysis of the dermo-epidermal surface in three-dimensions is important for evaluating cosmetics. One approach is based on the active contour model, which is used for extracting local object boundaries with closed curve form. The dermo-epidermal surface, however, is a plane with open form. We have developed a method of automatically extracting the dermo-epidermal surface from volumetric confocal microscopic images, as well as constructing a 3-D visual model of the surface by using the geometric information contained in the control points. Our method is a 3-D extension of the active contour model, so we call it the active open surface model (AOSM). The initial surface for AOSM is an open curve plane, guided by a 3-D internal force, a 3-D external constraint force, and a 3-D image force, which pull it toward the objective surface. The proposed technique has been applied to extract actual dermo-epidermal surface in the given volumetric confocal microscopic images.

Original languageEnglish
Pages (from-to)268-279
Number of pages12
JournalProceedings of SPIE - The International Society for Optical Engineering
Publication statusPublished - 2003
EventSixth International Conference on Quality Control by Artificial Vision - Gatlinburg, TN, United States
Duration: 2003 May 192003 May 22


  • Active contour model
  • Active open surface model
  • Confocal microscope
  • Construct
  • Dermis
  • Dermo-epidermal surface
  • Dynamic programming
  • Epidermis
  • Skin
  • Three-dimensions

ASJC Scopus subject areas

  • Electronic, Optical and Magnetic Materials
  • Condensed Matter Physics
  • Computer Science Applications
  • Applied Mathematics
  • Electrical and Electronic Engineering


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