TY - JOUR
T1 - A Case of Cowden's Disease Without Typical Skin Eruptions
AU - Hibi, Toshifumi
AU - Hayashi, Atsushi
AU - Takaishi, Hiromasa
AU - Inoue, Nagamu
AU - Ueno, Yoshitaka
AU - Hosoda, Yasuo
AU - Watanabe, Mamoru
AU - Ishii, Hiromasa
AU - Inoue, Takashi
AU - Mukai, Makio
PY - 1995
Y1 - 1995
N2 - A 21-year-old man was admitted to our hospital hoping for the follow-up of gastric polyps. X-ray and endoscopic examinations revealed multiple polypoid lesions in the esophagus, and multiple polyps in the stomach and colon. Esophageal epithelial thickening was demonstrated in the esophageal polypoid lesions. Gastric and colonic hyperplastic polyps were confirmed histologically. Although typical skin findings were absent, Cowden's disease was strongly suggested by clinical features such as adenoid appearance, goiter, arteriovenous malformation and gingival papillomatosis. Cowden's disease is characterized by multiple hyperplastic or hamartomatous development originating from three embryonic germ layers in the whole body. Cowden's disease is frequently complicated with malignant tumors and should be considered in the differential diagnosis of various diseases with gastrointestinal polyposis.
AB - A 21-year-old man was admitted to our hospital hoping for the follow-up of gastric polyps. X-ray and endoscopic examinations revealed multiple polypoid lesions in the esophagus, and multiple polyps in the stomach and colon. Esophageal epithelial thickening was demonstrated in the esophageal polypoid lesions. Gastric and colonic hyperplastic polyps were confirmed histologically. Although typical skin findings were absent, Cowden's disease was strongly suggested by clinical features such as adenoid appearance, goiter, arteriovenous malformation and gingival papillomatosis. Cowden's disease is characterized by multiple hyperplastic or hamartomatous development originating from three embryonic germ layers in the whole body. Cowden's disease is frequently complicated with malignant tumors and should be considered in the differential diagnosis of various diseases with gastrointestinal polyposis.
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U2 - 10.11280/gee1973b.37.65
DO - 10.11280/gee1973b.37.65
M3 - Article
AN - SCOPUS:85007749176
SN - 0387-1207
VL - 37
SP - 65
EP - 71
JO - Gastroenterological Endoscopy
JF - Gastroenterological Endoscopy
IS - 1
ER -