A case of Macular corneal dystrophy type II

Hajime Shinoda, Seiji Nii, Masakazu Yamada, Yu Nakamura, Yukihiko Mashima, Kenji Takagishi

Research output: Contribution to journalArticlepeer-review


Most cases of macular corneal dystrophy (MCD) can be classified as type 1, which is keratan sulfate (KS) negative, or type II (KS positive) by testing for the presence of KS in the cornea and in the serum. We examined a 55-year-old Japanese male who had MCD. Histochemical studies revealed that the patient's corneal stroma stained with anti-KS monoclonal antibody (5-D- 4). The KS level in the patient's serum, as determined by an enzyme-linked immunosorbent assay, was within the normal range. These results confirmed the diagnosis of MCD type II.

Original languageEnglish
Pages (from-to)956-958
Number of pages3
JournalFolia Ophthalmologica Japonica
Issue number11
Publication statusPublished - 1998 Dec 1


  • Anti-Keratan Sulfate Monoclonal Antibody
  • Corneal Keratan Sulfate
  • Macular Corneal Dystrophy
  • Serum Keratan Sulfate

ASJC Scopus subject areas

  • Ophthalmology


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