A case of mediastinal mature teratoma complicated by empyema due to rupture into the pleural cavity

Yoshihiko Ikeno, Ikuo Akutsu, Kazuhiko Hagane, Kazuki Mashio, Hiroyuki Sakio, Fumito Omi, Takeshi Hirabayashi, Akihiro Fujino, Kumiya Sugiyama, Yasutugu Fukusima, Yoshiki Ishii, Takeshi Fukuda

Research output: Contribution to journalArticlepeer-review


A 16-year-old female visited our hospital, complaining of cough, fever, and left precordial pain. Chest computed tomography showed a heterogeneous anterior mediastinal tumor measuring 7 cm in diameter and complete atelectasis in the lingula and lower lobe of the left lung. Magnetic resonance imaging also showed an area of intensity identical to that of adipose tissue in the anterior mediastinal tumor. Thus, empyema due to rupture of a mature teratoma was diagnosed. The empyema was treated with intra-pleural fibrinolytic therapy, drainage, and antibiotics. After confirming resolution of the empyema, we resected the anterior mediastinal tumor and pathologically diagnosed it as cystic mature teratoma. Histopathological examination showed glandular tissue resembling the pancreas, suggesting that the rupture had been caused by pancreatic enzymes in the tumor. Mediastinal mature teratoma carries a risk of serious complications developing due to rupture and the possibility of malignant transformation during the disease course. Thus, early surgical treatment is important.

Original languageEnglish
Pages (from-to)171-177
Number of pages7
JournalDokkyo Journal of Medical Sciences
Issue number2
Publication statusPublished - 2011 Jul
Externally publishedYes


  • Empyema
  • Mediastinal mature teratoma
  • Rupture

ASJC Scopus subject areas

  • General Medicine


Dive into the research topics of 'A case of mediastinal mature teratoma complicated by empyema due to rupture into the pleural cavity'. Together they form a unique fingerprint.

Cite this