A new reagent for activating carboxyl groups: diphenyl 2-oxo-3-oxazolinylphosphonate

Takehisa Kunieda, Yoshihiro Abe, Tsunehiko Higuchi, Masaaki Hirobe

Research output: Contribution to journalArticlepeer-review

36 Citations (Scopus)


Diphenyl 2-oxo-3-oxazolinylphosphonate serves as a carboxyl-activating reagent to permit a direct preparation of versatile intermediate, 3-acyl-2-oxazolones or a one-step formation of amides from carboxylic acids.

Original languageEnglish
Pages (from-to)1257-1258
Number of pages2
JournalTetrahedron Letters
Issue number13
Publication statusPublished - 1981

ASJC Scopus subject areas

  • Biochemistry
  • Drug Discovery
  • Organic Chemistry


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