A novel blood glucose monitoring system based on an ISFET biosensor and its application to a human 75 g oral glucose tolerance test

N. Ito; A. Saito; S. Miyamoto; S. Shinohara; T. Kuriyama; J. Kimura; T. Arai; M. Kikuchi; S. Kayashima; N. Nagata; O. Takatani

doi:10.1016/0925-4005(90)80256-Y

A novel blood glucose monitoring system based on an ISFET biosensor and its application to a human 75 g oral glucose tolerance test

N. Ito, A. Saito, S. Miyamoto, S. Shinohara, T. Kuriyama, J. Kimura, T. Arai, M. Kikuchi, S. Kayashima, N. Nagata, O. Takatani

Research output: Contribution to journal › Article › peer-review

12 Citations (Scopus)

Abstract

A novel blood glucose monitoring system was developed by applying an SOS/ISFET (silicon on sapphire/ion-sensitive field-effect transistor) biosensor to an SEF (suction effusion fluid). The effusion rate of the SEF was 11.9 ± 3.7 μlh^-1 cm^-2 and the measurement was made every 7.5 min. Glucose concentrations measured using SEF showed a good correlation with those measured by using serum with a slight delay of about 10 min. The blood glucose monitoring system was successfully applied to a non-invasive transcutaneous blood glucose monitoring on human 75 g oral glucose tolerance test. This result shows it will enable realization of a portable blood glucose monitoring device and the system will become very useful in medical treatment.

Original language	English
Pages (from-to)	488-490
Number of pages	3
Journal	Sensors and Actuators: B. Chemical
Volume	1
Issue number	1-6
DOIs	https://doi.org/10.1016/0925-4005(90)80256-Y
Publication status	Published - 1990 Jan
Externally published	Yes

ASJC Scopus subject areas

Electronic, Optical and Magnetic Materials
Instrumentation
Condensed Matter Physics
Surfaces, Coatings and Films
Metals and Alloys
Electrical and Electronic Engineering
Materials Chemistry

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10.1016/0925-4005(90)80256-Y

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Ito, N., Saito, A., Miyamoto, S., Shinohara, S., Kuriyama, T., Kimura, J., Arai, T., Kikuchi, M., Kayashima, S., Nagata, N., & Takatani, O. (1990). A novel blood glucose monitoring system based on an ISFET biosensor and its application to a human 75 g oral glucose tolerance test. Sensors and Actuators: B. Chemical, 1(1-6), 488-490. https://doi.org/10.1016/0925-4005(90)80256-Y

Ito, N, Saito, A, Miyamoto, S, Shinohara, S, Kuriyama, T, Kimura, J, Arai, T, Kikuchi, M, Kayashima, S, Nagata, N & Takatani, O 1990, 'A novel blood glucose monitoring system based on an ISFET biosensor and its application to a human 75 g oral glucose tolerance test', Sensors and Actuators: B. Chemical, vol. 1, no. 1-6, pp. 488-490. https://doi.org/10.1016/0925-4005(90)80256-Y

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abstract = "A novel blood glucose monitoring system was developed by applying an SOS/ISFET (silicon on sapphire/ion-sensitive field-effect transistor) biosensor to an SEF (suction effusion fluid). The effusion rate of the SEF was 11.9 ± 3.7 μlh-1 cm-2 and the measurement was made every 7.5 min. Glucose concentrations measured using SEF showed a good correlation with those measured by using serum with a slight delay of about 10 min. The blood glucose monitoring system was successfully applied to a non-invasive transcutaneous blood glucose monitoring on human 75 g oral glucose tolerance test. This result shows it will enable realization of a portable blood glucose monitoring device and the system will become very useful in medical treatment.",

author = "N. Ito and A. Saito and S. Miyamoto and S. Shinohara and T. Kuriyama and J. Kimura and T. Arai and M. Kikuchi and S. Kayashima and N. Nagata and O. Takatani",

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AU - Ito, N.

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AU - Shinohara, S.

AU - Kuriyama, T.

AU - Kimura, J.

AU - Arai, T.

AU - Kikuchi, M.

AU - Kayashima, S.

AU - Nagata, N.

AU - Takatani, O.

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AB - A novel blood glucose monitoring system was developed by applying an SOS/ISFET (silicon on sapphire/ion-sensitive field-effect transistor) biosensor to an SEF (suction effusion fluid). The effusion rate of the SEF was 11.9 ± 3.7 μlh-1 cm-2 and the measurement was made every 7.5 min. Glucose concentrations measured using SEF showed a good correlation with those measured by using serum with a slight delay of about 10 min. The blood glucose monitoring system was successfully applied to a non-invasive transcutaneous blood glucose monitoring on human 75 g oral glucose tolerance test. This result shows it will enable realization of a portable blood glucose monitoring device and the system will become very useful in medical treatment.

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A novel blood glucose monitoring system based on an ISFET biosensor and its application to a human 75 g oral glucose tolerance test

Abstract

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