A patient with diabetes mellitus and severe arterial embolism

Matsuhiko Hayashi, Ken Yajima, Hiroshi Maruyama, Kenji Matsumoto, Suguru Inokuchi, Eiji Ikeda

Research output: Contribution to journalArticlepeer-review


An 89-year-old man with diabetes mellitus was admitted to the hospital because of a low-grade fever and a disturbance in consciousness. He had been diagnosed as having diabetes mellitus at the age of 22 years and had been taking oral hypoglycemic drugs for 16 years at least. A few days before admission, a loss of appetite was noticed by his family; he developed a stupor on the day of admission. On physical examination, his lower extremities were pale and his skin temperature was low. Laboratory tests showed an increase in his white blood cell count and his blood culture was positive for Staphylococcus aureus. An MRI showed that the abdominal aorta was totally occluded beneath the renal arteries, and no significant collateral circulation was observed. He was given antibiotics and anticoagulants, but his general condition continued to worsen. Laboratory tests showed renal failure and liver dysfunction, indicating multi-organ failure. On the 24th day of admission, he died of respiratory and heart failure. An autopsy showed the aorta to be totally occluded beneath the renal arteries by an embolism; atherosclerotic changes were rather mild. Acute plaque change on the surface of the aorta may have induced the sudden development of emboli in the aorta.

Original languageEnglish
Pages (from-to)280-290
Number of pages11
JournalKeio Journal of Medicine
Issue number4
Publication statusPublished - 2001

ASJC Scopus subject areas

  • General Medicine


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