TY - JOUR
T1 - A randomized Phase III trial of thoracoscopic versus open esophagectomy for thoracic esophageal cancer
T2 - Japan Clinical Oncology Group Study JCOG1409
AU - Japan Esophageal Oncology Group/Japan Clinical Oncology Group
AU - Kataoka, Kozo
AU - Takeuchi, Hiroya
AU - Mizusawa, Junki
AU - Ando, Masahiko
AU - Tsubosa, Yasuhiro
AU - Koyanagi, Kazuo
AU - Daiko, Hiroyuki
AU - Matsuda, Satoru
AU - Nakamura, Kenichi
AU - Kato, Ken
AU - Kitagawa, Yuko
N1 - Publisher Copyright:
© The Author 2016.
PY - 2016/2/1
Y1 - 2016/2/1
N2 - A randomized Phase III study was commenced in May 2015 to confirm the non-inferiority of thoracoscopic esophagectomy to open esophagectomy in terms of overall survival for clinical Stage I-III esophageal cancer. A total of 300 patients will be accrued from Japanese institutions over 6 years. The primary endpoint is overall survival. The secondary endpoints are relapse-free survival, proportion of patients with R0 resection, proportion of patients who underwent re-operation, adverse events, postoperative respiratory function change, postoperative quality-of-life score (EORTC QLQC30), and proportion of patients who need conversion from thoracoscopic surgery to open surgery. This trial has been registered in the UMIN Clinical Trials Registry as UMIN000017628.
AB - A randomized Phase III study was commenced in May 2015 to confirm the non-inferiority of thoracoscopic esophagectomy to open esophagectomy in terms of overall survival for clinical Stage I-III esophageal cancer. A total of 300 patients will be accrued from Japanese institutions over 6 years. The primary endpoint is overall survival. The secondary endpoints are relapse-free survival, proportion of patients with R0 resection, proportion of patients who underwent re-operation, adverse events, postoperative respiratory function change, postoperative quality-of-life score (EORTC QLQC30), and proportion of patients who need conversion from thoracoscopic surgery to open surgery. This trial has been registered in the UMIN Clinical Trials Registry as UMIN000017628.
KW - Open esophagectomy
KW - Phase III
KW - Thoracoscopic esophagectomy
UR - http://www.scopus.com/inward/record.url?scp=84961612875&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=84961612875&partnerID=8YFLogxK
U2 - 10.1093/jjco/hyv178
DO - 10.1093/jjco/hyv178
M3 - Article
C2 - 26732383
AN - SCOPUS:84961612875
SN - 0368-2811
VL - 46
SP - 174
EP - 177
JO - Japanese journal of clinical oncology
JF - Japanese journal of clinical oncology
IS - 2
ER -
