A reticuloendothelial system-activating glycan from the barks ofEucommia ulmoides

Masashi Tomoda, Ryo ̃ko Gonda, Noriko Shimizu, Mieko Kanari

Research output: Contribution to journalArticlepeer-review

27 Citations (Scopus)


From the hot water extract of the barks ofEucommia ulmoides, a glycan, named eucomman B, has been isolated by treatment with cetyltrimethylammonium bromide followed by fractionation on DEAE-Sephadex A-25 and chromatography on Sephacryl S-300 columns. Chemical and spectroscopic studies established that the glycan possesses mainly α-1,2-linkedl-rhamno-α-1,4-linkedd-galacturonan structure. α-1,5-Linkedl-arabinofuranose, α-1,3-linkedl-arabinopyranose, β-1,3- and β-1,4-linkedd-galactose, 2,4-branchedl-rhamnose and 3,4-branchedd-galacturonic acid residues were also identified as the component sugar units. The glycan showed significant reticuloendothelial system potentiating activity in the carbon clearance test.

Original languageEnglish
Pages (from-to)3091-3094
Number of pages4
Issue number10
Publication statusPublished - 1990


  • Eucommia ulmoides
  • Eucommiaceae
  • bark
  • phagocytic activity.
  • polysaccharide
  • structural analysis

ASJC Scopus subject areas

  • Biochemistry
  • Molecular Biology
  • Plant Science
  • Horticulture


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