A reticuloendothelial system activating glycan from the rhizomes of Curcuma longa

Masashi Tomoda, Ryoko Gonda, Noriko Shimizu, Mieko Kanari, Miyako Kimura

Research output: Contribution to journalArticlepeer-review

30 Citations (Scopus)


From the hot water extract of the rhizomes of Curcuma longa, a glycan, named ukonan A, has been isolated by fractionation on DEAE-Sephadex A-25 followed by chromatography on Con A-Sepharose and Sephacryl S-300 columns. Chemical and spectroscopic studies established that the glycan possesses an α-l-arabino-3,6-β-d-galactan structure. α-1,3-Linked l-arabinopyranose, β-3,4-branched d-xylose, α-1,4-linked d-glucose, α-2,4-branched l-rhamnose and α-1,4-linked d-galacturonic acid residues were also identified as the component sugar units. The glycan showed remarkable reticuloendothelial system potentiating activity in the carbon clearance test.

Original languageEnglish
Pages (from-to)1083-1086
Number of pages4
Issue number4
Publication statusPublished - 1990


  • Curcuma longa
  • Zingiberaceae
  • phagocytic activity
  • polysaccharide
  • rhizome
  • structural analysis.

ASJC Scopus subject areas

  • Biochemistry
  • Molecular Biology
  • Plant Science
  • Horticulture


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