A synthesis of natural α-tocopherol intermediate

Takeshi Sugai; Naoyuki Watanabe; Hiromichi Ohta

doi:10.1016/S0957-4166(00)82122-9

A synthesis of natural α-tocopherol intermediate

Takeshi Sugai, Naoyuki Watanabe, Hiromichi Ohta

School of Pharmaceutical Sciences

Research output: Contribution to journal › Article › peer-review

28 Citations (Scopus)

Abstract

(S)-(-)-6-Hydroxy-2,5,7,8-tetramethyl-2-chromanmethanol, an intermediate of natural α-tocopherol was synthesized from (S)-2-benzyloxy-2-methyl-4-pentenoic acid, which was obtained by the enzymatic hydrolysis of the corresponding racemic methyl ester.

Original language	English
Pages (from-to)	371-376
Number of pages	6
Journal	Tetrahedron: Asymmetry
Volume	2
Issue number	5
DOIs	https://doi.org/10.1016/S0957-4166(00)82122-9
Publication status	Published - 1991

ASJC Scopus subject areas

Catalysis
Physical and Theoretical Chemistry
Organic Chemistry
Inorganic Chemistry

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10.1016/S0957-4166(00)82122-9

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title = "A synthesis of natural α-tocopherol intermediate",

abstract = "(S)-(-)-6-Hydroxy-2,5,7,8-tetramethyl-2-chromanmethanol, an intermediate of natural α-tocopherol was synthesized from (S)-2-benzyloxy-2-methyl-4-pentenoic acid, which was obtained by the enzymatic hydrolysis of the corresponding racemic methyl ester.",

author = "Takeshi Sugai and Naoyuki Watanabe and Hiromichi Ohta",

year = "1991",

doi = "10.1016/S0957-4166(00)82122-9",

language = "English",

volume = "2",

pages = "371--376",

journal = "Tetrahedron: Asymmetry",

issn = "0957-4166",

publisher = "Elsevier Limited",

number = "5",

}

TY - JOUR

T1 - A synthesis of natural α-tocopherol intermediate

AU - Sugai, Takeshi

AU - Watanabe, Naoyuki

AU - Ohta, Hiromichi

PY - 1991

Y1 - 1991

N2 - (S)-(-)-6-Hydroxy-2,5,7,8-tetramethyl-2-chromanmethanol, an intermediate of natural α-tocopherol was synthesized from (S)-2-benzyloxy-2-methyl-4-pentenoic acid, which was obtained by the enzymatic hydrolysis of the corresponding racemic methyl ester.

AB - (S)-(-)-6-Hydroxy-2,5,7,8-tetramethyl-2-chromanmethanol, an intermediate of natural α-tocopherol was synthesized from (S)-2-benzyloxy-2-methyl-4-pentenoic acid, which was obtained by the enzymatic hydrolysis of the corresponding racemic methyl ester.

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UR - http://www.scopus.com/inward/citedby.url?scp=0025904540&partnerID=8YFLogxK

U2 - 10.1016/S0957-4166(00)82122-9

DO - 10.1016/S0957-4166(00)82122-9

M3 - Article

AN - SCOPUS:0025904540

SN - 0957-4166

VL - 2

SP - 371

EP - 376

JO - Tetrahedron: Asymmetry

JF - Tetrahedron: Asymmetry

IS - 5

ER -

A synthesis of natural α-tocopherol intermediate

Abstract

ASJC Scopus subject areas

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