A synthesis of natural α-tocopherol intermediate

Takeshi Sugai, Naoyuki Watanabe, Hiromichi Ohta

Research output: Contribution to journalArticlepeer-review

28 Citations (Scopus)


(S)-(-)-6-Hydroxy-2,5,7,8-tetramethyl-2-chromanmethanol, an intermediate of natural α-tocopherol was synthesized from (S)-2-benzyloxy-2-methyl-4-pentenoic acid, which was obtained by the enzymatic hydrolysis of the corresponding racemic methyl ester.

Original languageEnglish
Pages (from-to)371-376
Number of pages6
JournalTetrahedron: Asymmetry
Issue number5
Publication statusPublished - 1991

ASJC Scopus subject areas

  • Catalysis
  • Physical and Theoretical Chemistry
  • Organic Chemistry
  • Inorganic Chemistry


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