Access to enantiomerically pure intermediates for (−)-geosmin synthesis starting from (4aS,5S)-4,4a,5,6,7,8-hexahydro-5-hydroxy-4a-methyl-naphthalen-2(3H)-one

Ken Ichi Fuhshuku, Takeshi Sugai

Research output: Contribution to journalArticlepeer-review

5 Citations (Scopus)

Abstract

Enantiomerically pure key intermediates for the synthesis of the natural enantiomer of geosmin were synthesized from (4aS,5S)-4,4a,5,6,7,8-hexahydro-5-hydroxy-4a-methylnaphthalen-2(3H)-one.

Original languageEnglish
Pages (from-to)2267-2272
Number of pages6
JournalBioscience, Biotechnology and Biochemistry
Volume66
Issue number10
DOIs
Publication statusPublished - 2002 Jan 1

Keywords

  • Cyclopropanation
  • Geosmin
  • Hydrogenation
  • Wieland-Miescher ketone

ASJC Scopus subject areas

  • Biotechnology
  • Analytical Chemistry
  • Biochemistry
  • Applied Microbiology and Biotechnology
  • Molecular Biology
  • Organic Chemistry

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