TY - JOUR
T1 - Acute onset olfactory/taste disorders are associated with a high viral burden in mild or asymptomatic SARS-CoV-2 infections
AU - for the Keio Donner Project
AU - Nakagawara, Kensuke
AU - Masaki, Katsunori
AU - Uwamino, Yoshifumi
AU - Kabata, Hiroki
AU - Uchida, Sho
AU - Uno, Shunsuke
AU - Asakura, Takanori
AU - Funakoshi, Takeru
AU - Kanzaki, Sho
AU - Ishii, Makoto
AU - Hasegawa, Naoki
AU - Fukunaga, Koichi
N1 - Publisher Copyright:
© 2020 The Author(s)
PY - 2020/10
Y1 - 2020/10
N2 - This study investigated, using cycle threshold (Ct) qPCR values, the association between symptoms and viral clearance in 57 patients with asymptomatic/mild SARS-CoV-2 infection. Patients with olfactory/taste disorders (OTDs) exhibited lower qPCR Ct values and longer time to negative qPCR than those without OTDs, suggesting an association between OTDs and high viral burden.
AB - This study investigated, using cycle threshold (Ct) qPCR values, the association between symptoms and viral clearance in 57 patients with asymptomatic/mild SARS-CoV-2 infection. Patients with olfactory/taste disorders (OTDs) exhibited lower qPCR Ct values and longer time to negative qPCR than those without OTDs, suggesting an association between OTDs and high viral burden.
KW - COVID-19
KW - Cycle threshold (Ct) values
KW - Olfactory/taste disorders (OTDs)
KW - Real-time polymerase chain reaction (qPCR)
KW - SARS-CoV-2
UR - http://www.scopus.com/inward/record.url?scp=85089521836&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=85089521836&partnerID=8YFLogxK
U2 - 10.1016/j.ijid.2020.07.034
DO - 10.1016/j.ijid.2020.07.034
M3 - Article
C2 - 32726723
AN - SCOPUS:85089521836
SN - 1201-9712
VL - 99
SP - 19
EP - 22
JO - International Journal of Infectious Diseases
JF - International Journal of Infectious Diseases
ER -