Acute regrowth and dissemination of a mature spinal cord teratoma after partial resection

Momotaro Kawai, Narihito Nagoshi, Akio Iwanami, Shuji Mikami, Osahiko Tsuji, Nobuyuki Fujita, Mitsuru Yagi, Kota Watanabe, Ken Ishii, Masaya Nakamura, Morio Matsumoto

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4 Citations (Scopus)


A 23-year-old man presented with difficulty walking and leg pain and numbness. MRI revealed a cystic mass at Th11-12 and a pineal-region tumour. The patient underwent surgery to resect the thoracic-level mass. The tumour adhered strongly to the neural tissue and could only be partially resected. On pathological examination, the resected tumour was diagnosed as a mature teratoma. The tumour regrew and disseminated within 3 months after resection. Both the spinal cord tumour and the tumour in the pineal region shrank significantly after chemotherapy and radiotherapy. Although the tumour was pathologically diagnosed as a mature teratoma, we suspect that the residual tumour contained an immature or malignant component. Thus, careful follow-up observation is mandatory after partial resection of a mature teratoma. In addition, because teratomas can disseminate in the central nervous system, the presence of teratoma should prompt an examination of both the spinal cord and brain.

Original languageEnglish
Article numberbcr-2017-223742
JournalBMJ case reports
Publication statusPublished - 2018


  • CNS cancer
  • neurosurgery
  • orthopaedic and trauma surgery
  • orthopaedics
  • spinal cord

ASJC Scopus subject areas

  • General Medicine


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