ADAMs 10 and 17 represent differentially regulated components of a general shedding machinery for membrane proteins such as transforming growth factor alpha, L-selectin, and tumor necrosis factor alpha.

Sylvain M. Le Gall, Pierre Bobé, Karina Reiss, Keisuke Horiuchi, Xiao Da Niu, Daniel Lundell, David R. Gibb, Daniel Conrad, Paul Saftig, Carl P. Blobel

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