Advanced hypopharyngeal cancer with amyotrophic lateral sclerosis

Yasunao Kogashiwa, Naoki Oishi, Kohichi Yamauchi, Naoyuki Kohno

Research output: Contribution to journalArticlepeer-review

3 Citations (Scopus)


We present a case of advanced hypopharyngeal cancer occurring in a patient with amyotrophic lateral sclerosis (ALS). A 58-year-old man diagnosed with ALS 2 years previously noticed a mass in his neck and dysphagia. We diagnosed him as having hypopharyngeal squamous cell carcinoma with the left cervical lymph node metastases (T3N2bM0) and treated with concurrent chemoradiotherapy. During and after the treatment, his neurological symptoms showed no worse signs. The patient has been cancer-free for 13 months after concurrent chemoradiotherapy. The influence of ALS on the patients' quality of life (QOL) and/or prognosis had to be taken into consideration when determining an appropriate treatment for the hypopharyngeal cancer. To the best of our knowledge, this may be the first case with ALS who was treated for hypopharyngeal cancer.

Original languageEnglish
Pages (from-to)750-752
Number of pages3
JournalAuris Nasus Larynx
Issue number6
Publication statusPublished - 2011 Dec
Externally publishedYes


  • Amyotrophic lateral sclerosis
  • Chemoradiotherapy
  • Hypopharyngeal cancer
  • Quality of life

ASJC Scopus subject areas

  • Surgery
  • Otorhinolaryngology


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