TY - JOUR
T1 - Alcohol Consumption and Coronary Artery Calcium in Middle-Aged Japanese Men
AU - Okamura, Tomonori
AU - Kadowaki, Takashi
AU - Sekikawa, Akira
AU - Murata, Kiyoshi
AU - Miyamatsu, Naomi
AU - Nakamura, Yasuyuki
AU - El-Saed, Aiman
AU - Kashiwagi, Atsunori
AU - Maegawa, Hiroshi
AU - Nishio, Yoshihiko
AU - Takamiya, Tomoko
AU - Kanda, Hideyuki
AU - Mitsunami, Kenichi
AU - Kita, Yoshikuni
AU - Edmundowicz, Daniel
AU - Tamaki, Shinji
AU - Tsujita, Yasuyuki
AU - Kuller, Lewis H.
AU - Ueshima, Hirotsugu
PY - 2006/7/15
Y1 - 2006/7/15
N2 - Epidemiologic studies have investigated the relation between alcohol intake and coronary calcification, with controversial results. Furthermore, the influence of heavy drinking has not been well elucidated. In the present study, a random sample of community-based Japanese men aged 40 to 49 years without a history of cardiovascular disease (n = 245) were examined for coronary artery calcium (CAC) determined by electron-beam computed tomography and drinking status. There was a J-shaped association between alcohol intake and CAC. There was an increase of CAC in heavy drinkers (≥46 g/day), and participants who were drinking ≥69 g/day showed a significant increase in CAC compared with never drinkers after adjusting for other cardiovascular risk factors.
AB - Epidemiologic studies have investigated the relation between alcohol intake and coronary calcification, with controversial results. Furthermore, the influence of heavy drinking has not been well elucidated. In the present study, a random sample of community-based Japanese men aged 40 to 49 years without a history of cardiovascular disease (n = 245) were examined for coronary artery calcium (CAC) determined by electron-beam computed tomography and drinking status. There was a J-shaped association between alcohol intake and CAC. There was an increase of CAC in heavy drinkers (≥46 g/day), and participants who were drinking ≥69 g/day showed a significant increase in CAC compared with never drinkers after adjusting for other cardiovascular risk factors.
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U2 - 10.1016/j.amjcard.2006.01.095
DO - 10.1016/j.amjcard.2006.01.095
M3 - Article
C2 - 16828581
AN - SCOPUS:33745651395
SN - 0002-9149
VL - 98
SP - 141
EP - 144
JO - American Journal of Cardiology
JF - American Journal of Cardiology
IS - 2
ER -