All-nanofiber-based, ultrasensitive, gas-permeable mechanoacoustic sensors for continuous long-term heart monitoring

Md Osman Goni Nayeem, Sunghoon Lee, Hanbit Jin, Naoji Matsuhisa, Hiroaki Jinno, Akihito Miyamoto, Tomoyuki Yokota, Takao Someya

Research output: Contribution to journalArticlepeer-review

114 Citations (Scopus)


The prolonged and continuous monitoring of mechanoacoustic heart signals is essential for the early diagnosis of cardiovascular diseases. These bodily acoustics have low intensity and low frequency, and measuring them continuously for long periods requires ultrasensitive, lightweight, gas-permeable mechanoacoustic sensors. Here, we present an all-nanofiber mechanoacoustic sensor, which exhibits a sensitivity as high as 10,050.6 mV Pa-1 in the lowfrequency region (<500 Hz). The high sensitivity is achieved by the use of durable and ultrathin (2.5 μm) nanofiber electrode layers enabling a large vibration of the sensor during the application of sound waves. The sensor is ultralightweight, and the overall weight is as small as 5 mg or less. The devices are mechanically robust against bending, and show no degradation in performance even after 1,000- cycle bending. Finally, we demonstrate a continuous long-term (10 h) measurement of heart signals with a signal-to-noise ratio as high as 40.9 decibels (dB).

Original languageEnglish
Pages (from-to)7063-7070
Number of pages8
JournalProceedings of the National Academy of Sciences of the United States of America
Issue number13
Publication statusPublished - 2020 Mar 31
Externally publishedYes


  • Biomedical devices
  • Gas-permeable sensors
  • Mechanoacoustic sensor
  • Wearable electronics

ASJC Scopus subject areas

  • General


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