Ambulatory blood pressure in prehypertensive children and adolescents

Hisayo Fujita, Seiji Matsuoka, Midori Awazu

Research output: Contribution to journalArticlepeer-review

5 Citations (Scopus)


Background Prehypertension is defined as blood pressure (BP) ≥90th percentile, or ≥120/80 mmHg, but <95th per-centile for age, sex, and height. Since the definition is made by conventional BP measurements and office BP can be quite variable, we studied whether prehypertension could be differentiated by ambulatory BP monitoring from normo-tension or hypertension (HTN) in children and adolescents. Methods One hundred and fifty-eight children (84 boys and 74 girls, aged 6-17 years, median 12) were studied. According to the office BP values, they were divided into normo-tension (80), prehypertension (20), and HTN (58). Results Systolic BP index and systolic daytime ambulatory BP (ABP) were significantly higher in prehypertensive patients than in normotensives and lower than hypertensives. When daytime ABP was used to diagnose HTN, four nor-motensive (5.0%), four prehypertensive (20.0%), and 27 hypertensive (46.6%) patients had HTN. Thus, in patients with prehypertension, the prevalence of masked HTN is significantly higher than in those with normotension. On the other hand, the prevalence of daytime ambulatory HTN is significantly lower, i.e., white-coat effect is more frequent, compared with hypertensive patients. Conclusion Prehypertension lies between normotension and HTN in ABP values as well and is a good candidate for identifying masked HTN. Our data emphasize the importance of identifying prehypertension in children and adolescents.

Original languageEnglish
Pages (from-to)1361-1367
Number of pages7
JournalPediatric Nephrology
Issue number8
Publication statusPublished - 2012 Aug
Externally publishedYes


  • Adolescents
  • Ambulatory blood pressure
  • Children
  • Hypertension
  • Masked hypertension
  • Prehypertension

ASJC Scopus subject areas

  • Pediatrics, Perinatology, and Child Health
  • Nephrology


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