Amidation reaction of carboxylic acid with formamide derivative using SO3•pyridine

Shota Kawano; Kodai Saito; Tohru Yamada

doi:10.1246/cl.171216

Amidation reaction of carboxylic acid with formamide derivative using SO₃•pyridine

Shota Kawano, Kodai Saito, Tohru Yamada

Department of Chemistry

Research output: Contribution to journal › Article › peer-review

4 Citations (Scopus)

Abstract

The amidation reaction of carboxylic acid derivatives was developed using sulfur trioxide pyridine complex (SO₃•py) as a commercially available and easily handled oxidant. This method could be applied to the reaction of various aromatic and aliphatic carboxylic acids, including optically active ones, with formamide derivatives to afford the corresponding amides in good to high yields.

Original language	English
Pages (from-to)	584-586
Number of pages	3
Journal	Chemistry Letters
Volume	47
Issue number	4
DOIs	https://doi.org/10.1246/cl.171216
Publication status	Published - 2018

Keywords

Amidation
Metal-free synthesis
Sulfur oxide

ASJC Scopus subject areas

Chemistry(all)

Access to Document

10.1246/cl.171216

Cite this

@article{e42b75cd71a14f8ea4a40ce890a536c6,

title = "Amidation reaction of carboxylic acid with formamide derivative using SO3•pyridine",

abstract = "The amidation reaction of carboxylic acid derivatives was developed using sulfur trioxide pyridine complex (SO3•py) as a commercially available and easily handled oxidant. This method could be applied to the reaction of various aromatic and aliphatic carboxylic acids, including optically active ones, with formamide derivatives to afford the corresponding amides in good to high yields.",

keywords = "Amidation, Metal-free synthesis, Sulfur oxide",

author = "Shota Kawano and Kodai Saito and Tohru Yamada",

note = "Publisher Copyright: {\textcopyright} 2018 The Chemical Society of Japan.",

year = "2018",

doi = "10.1246/cl.171216",

language = "English",

volume = "47",

pages = "584--586",

journal = "Chemistry Letters",

issn = "0366-7022",

publisher = "Chemical Society of Japan",

number = "4",

}

TY - JOUR

T1 - Amidation reaction of carboxylic acid with formamide derivative using SO3•pyridine

AU - Kawano, Shota

AU - Saito, Kodai

AU - Yamada, Tohru

PY - 2018

Y1 - 2018

N2 - The amidation reaction of carboxylic acid derivatives was developed using sulfur trioxide pyridine complex (SO3•py) as a commercially available and easily handled oxidant. This method could be applied to the reaction of various aromatic and aliphatic carboxylic acids, including optically active ones, with formamide derivatives to afford the corresponding amides in good to high yields.

AB - The amidation reaction of carboxylic acid derivatives was developed using sulfur trioxide pyridine complex (SO3•py) as a commercially available and easily handled oxidant. This method could be applied to the reaction of various aromatic and aliphatic carboxylic acids, including optically active ones, with formamide derivatives to afford the corresponding amides in good to high yields.

KW - Amidation

KW - Metal-free synthesis

KW - Sulfur oxide

UR - http://www.scopus.com/inward/record.url?scp=85045020295&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=85045020295&partnerID=8YFLogxK

U2 - 10.1246/cl.171216

DO - 10.1246/cl.171216

M3 - Article

AN - SCOPUS:85045020295

SN - 0366-7022

VL - 47

SP - 584

EP - 586

JO - Chemistry Letters

JF - Chemistry Letters

IS - 4

ER -