@inproceedings{72f075a1ad2a43c7af20f64a404d9d1e,
title = "An accurate method of extracting fat droplets in liver images for quantitative evaluation",
abstract = "The steatosis in liver pathological tissue images is a promising indicator of nonalcoholic fatty liver disease (NAFLD) and the possible risk of hepatocellular carcinoma (HCC). The resulting values are also important for ensuring the automatic and accurate classification of HCC images, because the existence of many fat droplets is likely to create errors in quantifying the morphological features used in the process. In this study we propose a method that can automatically detect, and exclude regions with many fat droplets by using the feature values of colors, shapes and the arrangement of cell nuclei. We implement the method and confirm that it can accurately detect fat droplets and quantify the fat droplet ratio of actual images. This investigation also clarifies the effective characteristics that contribute to accurate detection.",
keywords = "Extract of fat droplets, Histopathological tissue images, Quantification",
author = "Masahiro Ishikawa and Naoki Kobayashi and Hideki Komagata and Kazuma Shinoda and Masahiro Yamaguchi and Tokiya Abe and Akinori Hashiguchi and Michiie Sakamoto",
note = "Publisher Copyright: {\textcopyright} 2015 SPIE.; Medical Imaging 2015: Digital Pathology ; Conference date: 25-02-2015 Through 26-02-2015",
year = "2015",
doi = "10.1117/12.2081670",
language = "English",
series = "Progress in Biomedical Optics and Imaging - Proceedings of SPIE",
publisher = "SPIE",
editor = "Gurcan, {Metin N.} and Anant Madabhushi",
booktitle = "Medical Imaging 2015",
}