An Antitumor Morphinane Alkaloid, Sinococuline, from Cocculus trilobus

Hideji Itokawa, Shunji Tsuruoka, Koichi Takeya, Noboru Mori, Toru Sonobe, Seiji Kosemura, Toshinori Hamanaka

Research output: Contribution to journalArticlepeer-review

26 Citations (Scopus)


An antitumor morphinane alkaloid named sinococuline was isolated from the MeOH extract of Cocculus trilobus. Its structure was determined by spectroscopic analysis.

Original languageEnglish
Pages (from-to)1660-1662
Number of pages3
JournalChemical and Pharmaceutical Bulletin
Issue number4
Publication statusPublished - 1987
Externally publishedYes


  • Cocculus trilobus
  • Menispermaceae
  • NMR spectrum
  • antitumor substance
  • morphinane alkaloid
  • sinococuline

ASJC Scopus subject areas

  • Chemistry(all)
  • Drug Discovery


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