An Antitumor Morphinane Alkaloid, Sinococuline, from Cocculus trilobus

Hideji Itokawa; Shunji Tsuruoka; Koichi Takeya; Noboru Mori; Toru Sonobe; Seiji Kosemura; Toshinori Hamanaka

doi:10.1248/cpb.35.1660

An Antitumor Morphinane Alkaloid, Sinococuline, from Cocculus trilobus

Hideji Itokawa, Shunji Tsuruoka, Koichi Takeya, Noboru Mori, Toru Sonobe, Seiji Kosemura, Toshinori Hamanaka

Research output: Contribution to journal › Article › peer-review

26 Citations (Scopus)

Abstract

An antitumor morphinane alkaloid named sinococuline was isolated from the MeOH extract of Cocculus trilobus. Its structure was determined by spectroscopic analysis.

Original language	English
Pages (from-to)	1660-1662
Number of pages	3
Journal	Chemical and Pharmaceutical Bulletin
Volume	35
Issue number	4
DOIs	https://doi.org/10.1248/cpb.35.1660
Publication status	Published - 1987
Externally published	Yes

Keywords

Cocculus trilobus
Menispermaceae
NMR spectrum
antitumor substance
morphinane alkaloid
sinococuline

ASJC Scopus subject areas

Chemistry(all)
Drug Discovery

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10.1248/cpb.35.1660

Cite this

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title = "An Antitumor Morphinane Alkaloid, Sinococuline, from Cocculus trilobus",

abstract = "An antitumor morphinane alkaloid named sinococuline was isolated from the MeOH extract of Cocculus trilobus. Its structure was determined by spectroscopic analysis.",

keywords = "Cocculus trilobus, Menispermaceae, NMR spectrum, antitumor substance, morphinane alkaloid, sinococuline",

author = "Hideji Itokawa and Shunji Tsuruoka and Koichi Takeya and Noboru Mori and Toru Sonobe and Seiji Kosemura and Toshinori Hamanaka",

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T1 - An Antitumor Morphinane Alkaloid, Sinococuline, from Cocculus trilobus

AU - Itokawa, Hideji

AU - Tsuruoka, Shunji

AU - Takeya, Koichi

AU - Mori, Noboru

AU - Sonobe, Toru

AU - Kosemura, Seiji

AU - Hamanaka, Toshinori

PY - 1987

Y1 - 1987

N2 - An antitumor morphinane alkaloid named sinococuline was isolated from the MeOH extract of Cocculus trilobus. Its structure was determined by spectroscopic analysis.

AB - An antitumor morphinane alkaloid named sinococuline was isolated from the MeOH extract of Cocculus trilobus. Its structure was determined by spectroscopic analysis.

KW - Cocculus trilobus

KW - Menispermaceae

KW - NMR spectrum

KW - antitumor substance

KW - morphinane alkaloid

KW - sinococuline

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DO - 10.1248/cpb.35.1660

M3 - Article

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An Antitumor Morphinane Alkaloid, Sinococuline, from Cocculus trilobus

Abstract

Keywords

ASJC Scopus subject areas

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