An autopsy cases of δ agent positive hepatocellular carcinoma with livee cirrhosis

Hideaki Yasui; Yohei Fujitani; Haruhiko Sugimura; Hiromu Aoyama; Junji Shiga; Wataru Mori; Okio Hino; Shusuke Furuhashi; Kiyohiko Kurai

doi:10.2957/kanzo.28.466

An autopsy cases of δ agent positive hepatocellular carcinoma with livee cirrhosis

Hideaki Yasui, Yohei Fujitani, Haruhiko Sugimura, Hiromu Aoyama, Junji Shiga, Wataru Mori, Okio Hino, Shusuke Furuhashi, Kiyohiko Kurai

Research output: Contribution to journal › Article › peer-review

Abstract

An autopsy case of δ agent positive hepatocellular carcinoma with liver cirrhosis of 38-year-old female was reported. In 1974, the patient who was HBsAg carrier received blood transfusion for blood loss during delivery in Hong Kong at 27 year old. Two months later she was admitted to a hospital because of acute hepatitis. Liver biopsy performed in 1976 in U.S.A. revealed chronic hepatitis due to HBV. In 1981, she was referred to Tokyo University Hospital. Her serological examination showed positive HBsAg, HBcAb, HBeAb and δAb. By wedge biopsy liver cirrhosis with positive δ antigen in the nuclei of hepatocytes was demonstrated. In 1985, she died because of hepatocellular carcinoma. At autopsy, HBsAg was observed in liver tissue, but no 8 antigen was found. DNA of hepatitis B virus was not integrated in DNA of cancer cells. This is the second autopsy case of δ agent positive hepatocellular carcinoma in Japan.

Original language	English
Pages (from-to)	466-471
Number of pages	6
Journal	Kanzo
Volume	28
Issue number	4
DOIs	https://doi.org/10.2957/kanzo.28.466
Publication status	Published - 1987
Externally published	Yes

ASJC Scopus subject areas

Hepatology

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

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10.2957/kanzo.28.466

Cite this

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title = "An autopsy cases of δ agent positive hepatocellular carcinoma with livee cirrhosis",

abstract = "An autopsy case of δ agent positive hepatocellular carcinoma with liver cirrhosis of 38-year-old female was reported. In 1974, the patient who was HBsAg carrier received blood transfusion for blood loss during delivery in Hong Kong at 27 year old. Two months later she was admitted to a hospital because of acute hepatitis. Liver biopsy performed in 1976 in U.S.A. revealed chronic hepatitis due to HBV. In 1981, she was referred to Tokyo University Hospital. Her serological examination showed positive HBsAg, HBcAb, HBeAb and δAb. By wedge biopsy liver cirrhosis with positive δ antigen in the nuclei of hepatocytes was demonstrated. In 1985, she died because of hepatocellular carcinoma. At autopsy, HBsAg was observed in liver tissue, but no 8 antigen was found. DNA of hepatitis B virus was not integrated in DNA of cancer cells. This is the second autopsy case of δ agent positive hepatocellular carcinoma in Japan.",

author = "Hideaki Yasui and Yohei Fujitani and Haruhiko Sugimura and Hiromu Aoyama and Junji Shiga and Wataru Mori and Okio Hino and Shusuke Furuhashi and Kiyohiko Kurai",

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doi = "10.2957/kanzo.28.466",

language = "English",

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publisher = "Japan Society of Hepatology",

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T1 - An autopsy cases of δ agent positive hepatocellular carcinoma with livee cirrhosis

AU - Yasui, Hideaki

AU - Fujitani, Yohei

AU - Sugimura, Haruhiko

AU - Aoyama, Hiromu

AU - Shiga, Junji

AU - Mori, Wataru

AU - Hino, Okio

AU - Furuhashi, Shusuke

AU - Kurai, Kiyohiko

PY - 1987

Y1 - 1987

N2 - An autopsy case of δ agent positive hepatocellular carcinoma with liver cirrhosis of 38-year-old female was reported. In 1974, the patient who was HBsAg carrier received blood transfusion for blood loss during delivery in Hong Kong at 27 year old. Two months later she was admitted to a hospital because of acute hepatitis. Liver biopsy performed in 1976 in U.S.A. revealed chronic hepatitis due to HBV. In 1981, she was referred to Tokyo University Hospital. Her serological examination showed positive HBsAg, HBcAb, HBeAb and δAb. By wedge biopsy liver cirrhosis with positive δ antigen in the nuclei of hepatocytes was demonstrated. In 1985, she died because of hepatocellular carcinoma. At autopsy, HBsAg was observed in liver tissue, but no 8 antigen was found. DNA of hepatitis B virus was not integrated in DNA of cancer cells. This is the second autopsy case of δ agent positive hepatocellular carcinoma in Japan.

AB - An autopsy case of δ agent positive hepatocellular carcinoma with liver cirrhosis of 38-year-old female was reported. In 1974, the patient who was HBsAg carrier received blood transfusion for blood loss during delivery in Hong Kong at 27 year old. Two months later she was admitted to a hospital because of acute hepatitis. Liver biopsy performed in 1976 in U.S.A. revealed chronic hepatitis due to HBV. In 1981, she was referred to Tokyo University Hospital. Her serological examination showed positive HBsAg, HBcAb, HBeAb and δAb. By wedge biopsy liver cirrhosis with positive δ antigen in the nuclei of hepatocytes was demonstrated. In 1985, she died because of hepatocellular carcinoma. At autopsy, HBsAg was observed in liver tissue, but no 8 antigen was found. DNA of hepatitis B virus was not integrated in DNA of cancer cells. This is the second autopsy case of δ agent positive hepatocellular carcinoma in Japan.

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ER -

An autopsy cases of δ agent positive hepatocellular carcinoma with livee cirrhosis

Abstract

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UN SDGs

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