An overview of the total synthesis of africane-type sesquiterpenoids

Yutaka Matsuda, Yoko Saikawa, Masaya Nakata

Research output: Contribution to journalReview articlepeer-review

6 Citations (Scopus)


Africane-type sesquiterpenoids consist of a bicyclo[5.3.0]decane structure and have been isolated from various natural environments. Their characteristic C–C bond motifs, including a seven-membered ring core, fascinate many synthetic organic chemists. Thirteen total syntheses have been reported over the past four decades. The purpose of this digest is to provide an overview of these total syntheses of africane-type sesquiterpenoids, with an emphasis on methods for constructing the seven-membered ring structure.

Original languageEnglish
Pages (from-to)2377-2386
Number of pages10
JournalTetrahedron Letters
Issue number25
Publication statusPublished - 2018 Jun 20


  • Africane
  • Medium-sized ring formation
  • Sesquiterpenoids
  • Total synthesis

ASJC Scopus subject areas

  • Biochemistry
  • Drug Discovery
  • Organic Chemistry


Dive into the research topics of 'An overview of the total synthesis of africane-type sesquiterpenoids'. Together they form a unique fingerprint.

Cite this