An unusual iodinated 5′-deoxyxylofuranosyl nucleoside from an Okinawan Ascidian, Diplosoma sp.

Pulpi Margiastuti; Takayuki Ogi; Toshiaki Teruya; Junsei Taira; Kiyotake Suenaga; Katsuhiro Ueda

doi:10.1246/cl.2008.448

An unusual iodinated 5′-deoxyxylofuranosyl nucleoside from an Okinawan Ascidian, Diplosoma sp.

Pulpi Margiastuti, Takayuki Ogi, Toshiaki Teruya, Junsei Taira, Kiyotake Suenaga, Katsuhiro Ueda

Department of Chemistry

Research output: Contribution to journal › Article › peer-review

11 Citations (Scopus)

Abstract

An unusual nucleoside, 4-amino-7-(5′-deoxy-β-D-xylofuranosyl)-5- iodopyrrolo[2,3-d]pyrimidine (1), was isolated from an ascidian, Diplosoma sp., and its structure was successfully determined by spectroscopic and chemical analysis. The known didemnenones 2-5 were also isolated. Compound 1 was found to inhibit the division of fertilized sea urchin eggs.

Original language	English
Pages (from-to)	448-449
Number of pages	2
Journal	Chemistry Letters
Volume	37
Issue number	4
DOIs	https://doi.org/10.1246/cl.2008.448
Publication status	Published - 2008 Apr 5

ASJC Scopus subject areas

Chemistry(all)

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10.1246/cl.2008.448

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abstract = "An unusual nucleoside, 4-amino-7-(5′-deoxy-β-D-xylofuranosyl)-5- iodopyrrolo[2,3-d]pyrimidine (1), was isolated from an ascidian, Diplosoma sp., and its structure was successfully determined by spectroscopic and chemical analysis. The known didemnenones 2-5 were also isolated. Compound 1 was found to inhibit the division of fertilized sea urchin eggs.",

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AU - Teruya, Toshiaki

AU - Taira, Junsei

AU - Suenaga, Kiyotake

AU - Ueda, Katsuhiro

PY - 2008/4/5

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AB - An unusual nucleoside, 4-amino-7-(5′-deoxy-β-D-xylofuranosyl)-5- iodopyrrolo[2,3-d]pyrimidine (1), was isolated from an ascidian, Diplosoma sp., and its structure was successfully determined by spectroscopic and chemical analysis. The known didemnenones 2-5 were also isolated. Compound 1 was found to inhibit the division of fertilized sea urchin eggs.

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An unusual iodinated 5′-deoxyxylofuranosyl nucleoside from an Okinawan Ascidian, Diplosoma sp.

Abstract

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