TY - GEN
T1 - Analysis on Internal Biomolcular Network Structure of ATP-Drive Actomyosin-Collagen Hybrid Actuator
AU - Kohno, Kenjiro
AU - Hiratsuka, Yuichi
AU - Onoe, Hiroaki
N1 - Publisher Copyright:
© 2021 IEEE.
PY - 2021/6/20
Y1 - 2021/6/20
N2 - We investigated the relationship between the deformation of the molecular network of myosin and actin and the macroscopic actuator contraction. Although several bioactuators using actomyosin have been reported in the past, the relationship between the molecular-scale structure and the motion of actomyosin actuators remains largely unexplored. We stained for actin, myosin, and collagen, respectively, and observed the internal biomolecular structure of the actuator by fluorescence observation. We took time-lapse images of the contraction of fluorescently stained actuators and determined the molecular contraction ratio of actomyosin. Finally, the macro and micro contraction ratios of the actuators were compared and examined to understand the internal mechanism of the actomyosin-collagen bioactuator.
AB - We investigated the relationship between the deformation of the molecular network of myosin and actin and the macroscopic actuator contraction. Although several bioactuators using actomyosin have been reported in the past, the relationship between the molecular-scale structure and the motion of actomyosin actuators remains largely unexplored. We stained for actin, myosin, and collagen, respectively, and observed the internal biomolecular structure of the actuator by fluorescence observation. We took time-lapse images of the contraction of fluorescently stained actuators and determined the molecular contraction ratio of actomyosin. Finally, the macro and micro contraction ratios of the actuators were compared and examined to understand the internal mechanism of the actomyosin-collagen bioactuator.
KW - Actomyosin
KW - Collagen
KW - Fluorescent observation
KW - Motor protein
KW - Soft actuator
UR - http://www.scopus.com/inward/record.url?scp=85114965551&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=85114965551&partnerID=8YFLogxK
U2 - 10.1109/Transducers50396.2021.9495488
DO - 10.1109/Transducers50396.2021.9495488
M3 - Conference contribution
AN - SCOPUS:85114965551
T3 - 21st International Conference on Solid-State Sensors, Actuators and Microsystems, TRANSDUCERS 2021
SP - 651
EP - 654
BT - 21st International Conference on Solid-State Sensors, Actuators and Microsystems, TRANSDUCERS 2021
PB - Institute of Electrical and Electronics Engineers Inc.
T2 - 21st International Conference on Solid-State Sensors, Actuators and Microsystems, TRANSDUCERS 2021
Y2 - 20 June 2021 through 25 June 2021
ER -