Anthraquinone derivatives as a new family of protein photocleavers

Akane Suzuki, Masashi Hasegawa, Maiko Ishii, Shuichi Matsumura, Kazunobu Toshima

Research output: Contribution to journalArticlepeer-review

45 Citations (Scopus)


Certain anthraquinones, which are present in many biologically important natural products, effectively and randomly cleaved proteins (BSA or Lyso) during photoirradiation using a long wavelength UV light without any further additives. It was also found that this ability could be improved by the attachment of a suitable substituent into the anthraquinone core skeleton.

Original languageEnglish
Pages (from-to)4624-4627
Number of pages4
JournalBioorganic and Medicinal Chemistry Letters
Issue number20
Publication statusPublished - 2005 Oct 15


  • Anthraquinone
  • Cleavage
  • Hybrid
  • Photoirradiation
  • Protein

ASJC Scopus subject areas

  • Biochemistry
  • Molecular Medicine
  • Molecular Biology
  • Pharmaceutical Science
  • Drug Discovery
  • Clinical Biochemistry
  • Organic Chemistry


Dive into the research topics of 'Anthraquinone derivatives as a new family of protein photocleavers'. Together they form a unique fingerprint.

Cite this