Antimicrobial susceptibility of Chlamydia pneumoniae isolates from children and their families

Teruko Komoda; Hisaichi Bannai; Toshikatsu Hagiwara; Satoshi Iwata; Hironobu Akita; Yoshitake Satou; Takao Yokota; Keisuke Sunakawa

Antimicrobial susceptibility of Chlamydia pneumoniae isolates from children and their families

Teruko Komoda, Hisaichi Bannai, Toshikatsu Hagiwara, Satoshi Iwata, Hironobu Akita, Yoshitake Satou, Takao Yokota, Keisuke Sunakawa

Research output: Contribution to journal › Article › peer-review

Abstract

Eighteen isolates of Chlamydia pneumoniae from ill children with bronchitis and/or pneumonia and their families were tested in terms of susceptibility to antimicrobial agents. (These strains were isolated from May 1992 to December 1995). The antibiotics used were doxycline (DOXY), erythromycin (EM), rokitamycin (RKM), azithromycin (AZM), clarithromycin (CAM), roxithromycin (RXM) and ofloxacin (OFLX). The MIC ranges of these antibiotics against the isolates wee 0.03~0.125 μg/ml except OFLX (0.5~2.5 μg/ml), and the MICs were similar to those for C. pneumoniae TW 183 and C. trachomatis serovar L2. The minimal chlamydiacidal concentration was also determined by using 10 isolates for which the concentration was about 10 times higher than the MIC. No difference was found among the isolates from the same patients.

Original language	English
Pages (from-to)	205-209
Number of pages	5
Journal	Japanese Journal of Chemotherapy
Volume	46
Issue number	6
Publication status	Published - 1998
Externally published	Yes

Keywords

Antibiotics
Children
Chlamydia pneumoniae
Isolation

ASJC Scopus subject areas

Pharmacology
Pharmacology (medical)

Cite this

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title = "Antimicrobial susceptibility of Chlamydia pneumoniae isolates from children and their families",

abstract = "Eighteen isolates of Chlamydia pneumoniae from ill children with bronchitis and/or pneumonia and their families were tested in terms of susceptibility to antimicrobial agents. (These strains were isolated from May 1992 to December 1995). The antibiotics used were doxycline (DOXY), erythromycin (EM), rokitamycin (RKM), azithromycin (AZM), clarithromycin (CAM), roxithromycin (RXM) and ofloxacin (OFLX). The MIC ranges of these antibiotics against the isolates wee 0.03~0.125 μg/ml except OFLX (0.5~2.5 μg/ml), and the MICs were similar to those for C. pneumoniae TW 183 and C. trachomatis serovar L2. The minimal chlamydiacidal concentration was also determined by using 10 isolates for which the concentration was about 10 times higher than the MIC. No difference was found among the isolates from the same patients.",

keywords = "Antibiotics, Children, Chlamydia pneumoniae, Isolation",

author = "Teruko Komoda and Hisaichi Bannai and Toshikatsu Hagiwara and Satoshi Iwata and Hironobu Akita and Yoshitake Satou and Takao Yokota and Keisuke Sunakawa",

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language = "English",

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journal = "Japanese Journal of Chemotherapy",

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TY - JOUR

T1 - Antimicrobial susceptibility of Chlamydia pneumoniae isolates from children and their families

AU - Komoda, Teruko

AU - Bannai, Hisaichi

AU - Hagiwara, Toshikatsu

AU - Iwata, Satoshi

AU - Akita, Hironobu

AU - Satou, Yoshitake

AU - Yokota, Takao

AU - Sunakawa, Keisuke

PY - 1998

Y1 - 1998

N2 - Eighteen isolates of Chlamydia pneumoniae from ill children with bronchitis and/or pneumonia and their families were tested in terms of susceptibility to antimicrobial agents. (These strains were isolated from May 1992 to December 1995). The antibiotics used were doxycline (DOXY), erythromycin (EM), rokitamycin (RKM), azithromycin (AZM), clarithromycin (CAM), roxithromycin (RXM) and ofloxacin (OFLX). The MIC ranges of these antibiotics against the isolates wee 0.03~0.125 μg/ml except OFLX (0.5~2.5 μg/ml), and the MICs were similar to those for C. pneumoniae TW 183 and C. trachomatis serovar L2. The minimal chlamydiacidal concentration was also determined by using 10 isolates for which the concentration was about 10 times higher than the MIC. No difference was found among the isolates from the same patients.

AB - Eighteen isolates of Chlamydia pneumoniae from ill children with bronchitis and/or pneumonia and their families were tested in terms of susceptibility to antimicrobial agents. (These strains were isolated from May 1992 to December 1995). The antibiotics used were doxycline (DOXY), erythromycin (EM), rokitamycin (RKM), azithromycin (AZM), clarithromycin (CAM), roxithromycin (RXM) and ofloxacin (OFLX). The MIC ranges of these antibiotics against the isolates wee 0.03~0.125 μg/ml except OFLX (0.5~2.5 μg/ml), and the MICs were similar to those for C. pneumoniae TW 183 and C. trachomatis serovar L2. The minimal chlamydiacidal concentration was also determined by using 10 isolates for which the concentration was about 10 times higher than the MIC. No difference was found among the isolates from the same patients.

KW - Antibiotics

KW - Children

KW - Chlamydia pneumoniae

KW - Isolation

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SN - 1340-7007

VL - 46

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EP - 209

JO - Japanese Journal of Chemotherapy

JF - Japanese Journal of Chemotherapy

IS - 6

ER -

Antimicrobial susceptibility of Chlamydia pneumoniae isolates from children and their families

Abstract

Keywords

ASJC Scopus subject areas

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