Asian Pacific cooperative study of allogeneic bone marrow transplantation

Toru Masaoka, Akira Hiraoka, Sinichiro Okamoto, Yosihisa Kodera, Lu Xien Cao, Dao Pei Lu, Yao Chan Chen, Po Min Chen, Dong Jip Kim, Edmond Chiu, Raymond Liang, Alan Teh

Research output: Contribution to journalArticlepeer-review

1 Citation (Scopus)


The first cooperative study of the Asian Pacific bone marrow transplantation group included 75 patients with early leukemia who received human leukocyte antigen-matched sibling bone marrow transplants and were randomized into granulocyte colony-stimulating factor and control groups. The selected patients were registered from 10 centers in six countries and areas within Asia (Beijing, Taipei, Hong Kong, Japan, Korea, and Malaysia). The incidence of grades II-IV acute graft-vs.-host disease was 22.2%, and the 2-year survival rate was 62.7%. The period of protective isolation (27.1-66.7 days), period of hospitalization (38.6-130.5 days), and medical costs for 4 months (US $10,300-US $80,803) varied considerably. Good cooperation, i.e., low rate of protocol violation or rapid and precise presentation of case reports, was obtained.

Original languageEnglish
Pages (from-to)190-192
Number of pages3
JournalInternational journal of hematology
Issue number3
Publication statusPublished - 1999
Externally publishedYes


  • Asian bone marrow transplantation
  • Bone marrow transplantation costs
  • Granulocyte colony-stimulating factor
  • Period of hospitalization

ASJC Scopus subject areas

  • Hematology


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