Association of serum BDNF concentration with high-intensity interval training

Koichiro Azuma, Yusuke Osawa, Shogo Tabata, Shiori Horisawa, Fuminori Katsukawa, Hiroyuki Ishida, Yuko Oguma, Toshihide Kawai, Shuji Oguchi, Atsumi Ota, Haruhito Kikuchi, Mitsuru Murata, Hideo Matsumoto

Research output: Contribution to journalArticlepeer-review

1 Citation (Scopus)

Abstract

To evaluate the association of serum BDNF concentration with high-intensity interval training, 12 healthy male volunteers, aged 28-48 years, completed 16-week high-intensity interval training (HIIT) using ergometer. Training program consisted of >90% VO2 peak for 60 sec separated by 60 sec active rest period for 8-12 sets twice weekly for 16-week. Maximal exercise tolerance tests were performed before (0-week), 4-week, and 16-week after the intervention program. VO2 peak as well as peak watt was linearly increased after 4-week (9% for both VO2 peak and peak watt) and 16-week HIIT training (15% for VO2 peak and 18% for peak watt, p<0.01). However, there was no change in serum BDNF concentration by HIIT. On the other hand, there was a positive association of serum BDNF concentration at baseline with % increase in peak watt after the intervention (ρ=0.60, p<0.05). The association between BDNF and exercise training is still unclear, and more studies are needed to clarify the above positive association.

Original languageEnglish
Pages (from-to)227-232
Number of pages6
JournalJapanese Journal of Physical Fitness and Sports Medicine
Volume64
Issue number2
DOIs
Publication statusPublished - 2015

Keywords

  • Aerobic fitness
  • BDNF
  • High-intensity interval training

ASJC Scopus subject areas

  • Orthopedics and Sports Medicine
  • Physical Therapy, Sports Therapy and Rehabilitation

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