Asymmetric Hydrolysis of 1-Cyanoalkyl Acetates

Hiromichi Ohta, Satoshi Hiraga, Kenji Miyamoto, Gen ichi Tsuchihashi

Research output: Contribution to journalArticlepeer-review


Microorganisms that enantioselectively hydrolyze 1-cyanoalkyl acetates (aldehyde cyanohydrin) were screened. Candida tropicalis was found to be the best. The enzyme system of this strain catalyzed the enantioselective hydrolysis of (S)-isomers, leaving behind the (R)-acetates. The optical purities of recovered acetates were high as a chiral shift reagent.

Original languageEnglish
Pages (from-to)3023-3027
Number of pages5
JournalAgricultural and biological chemistry
Issue number12
Publication statusPublished - 1988

ASJC Scopus subject areas

  • Biochemistry, Genetics and Molecular Biology(all)
  • Agricultural and Biological Sciences(all)


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