Bilateral Adrenal Hyperplasia Due to Adrenocorticotropic Hormone-Secreting Esthesioneuroblastoma on FDG PET and 111In-Pentetreotide Scintigraphy

Yohji Matsusaka; Tadaki Nakahara; Isao Kurihara; Yu Iwabuchi; Masahiro Jinzaki

doi:10.1097/RLU.0000000000002081

Bilateral Adrenal Hyperplasia Due to Adrenocorticotropic Hormone-Secreting Esthesioneuroblastoma on FDG PET and 111In-Pentetreotide Scintigraphy

Yohji Matsusaka, Tadaki Nakahara, Isao Kurihara, Yu Iwabuchi, Masahiro Jinzaki

Research output: Contribution to journal › Article › peer-review

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Abstract

A 53-year-old woman with metastatic esthesioneuroblastoma was referred for FDG PET/CT imaging. FDG PET/CT showed symmetrical uptake in bilaterally enlarged adrenal glands, in addition to abnormal uptake in bone and lymph node metastases. ¹¹¹In-pentetreotide scintigraphy was further performed and revealed the lack of adrenal uptake. The patient's serum adrenocorticotropic hormone (ACTH) level was extremely high, suggesting that hyperplastic condition in the adrenal glands due to ACTH stimulation from the metastatic esthesioneuroblastoma was responsible for increased FDG uptake. The combination of FDG PET and ¹¹¹In-pentetreotide scintigraphy was useful for the pathophysiological evaluation of ACTH-secreting esthesioneuroblastoma.

Original language	English
Pages (from-to)	452-453
Number of pages	2
Journal	Clinical nuclear medicine
Volume	43
Issue number	6
DOIs	https://doi.org/10.1097/RLU.0000000000002081
Publication status	Published - 2018 Jun 1

Keywords

ACTH-secreting esthesioneuroblastoma
FDG PET
In pentetreotide scintigraphy
adrenal hyperplasia

ASJC Scopus subject areas

Radiology Nuclear Medicine and imaging

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10.1097/RLU.0000000000002081

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title = "Bilateral Adrenal Hyperplasia Due to Adrenocorticotropic Hormone-Secreting Esthesioneuroblastoma on FDG PET and 111In-Pentetreotide Scintigraphy",

abstract = "A 53-year-old woman with metastatic esthesioneuroblastoma was referred for FDG PET/CT imaging. FDG PET/CT showed symmetrical uptake in bilaterally enlarged adrenal glands, in addition to abnormal uptake in bone and lymph node metastases. 111In-pentetreotide scintigraphy was further performed and revealed the lack of adrenal uptake. The patient's serum adrenocorticotropic hormone (ACTH) level was extremely high, suggesting that hyperplastic condition in the adrenal glands due to ACTH stimulation from the metastatic esthesioneuroblastoma was responsible for increased FDG uptake. The combination of FDG PET and 111In-pentetreotide scintigraphy was useful for the pathophysiological evaluation of ACTH-secreting esthesioneuroblastoma.",

keywords = "ACTH-secreting esthesioneuroblastoma, FDG PET, In pentetreotide scintigraphy, adrenal hyperplasia",

author = "Yohji Matsusaka and Tadaki Nakahara and Isao Kurihara and Yu Iwabuchi and Masahiro Jinzaki",

year = "2018",

month = jun,

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doi = "10.1097/RLU.0000000000002081",

language = "English",

volume = "43",

pages = "452--453",

journal = "Clinical nuclear medicine",

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T1 - Bilateral Adrenal Hyperplasia Due to Adrenocorticotropic Hormone-Secreting Esthesioneuroblastoma on FDG PET and 111In-Pentetreotide Scintigraphy

AU - Matsusaka, Yohji

AU - Nakahara, Tadaki

AU - Kurihara, Isao

AU - Iwabuchi, Yu

AU - Jinzaki, Masahiro

PY - 2018/6/1

Y1 - 2018/6/1

N2 - A 53-year-old woman with metastatic esthesioneuroblastoma was referred for FDG PET/CT imaging. FDG PET/CT showed symmetrical uptake in bilaterally enlarged adrenal glands, in addition to abnormal uptake in bone and lymph node metastases. 111In-pentetreotide scintigraphy was further performed and revealed the lack of adrenal uptake. The patient's serum adrenocorticotropic hormone (ACTH) level was extremely high, suggesting that hyperplastic condition in the adrenal glands due to ACTH stimulation from the metastatic esthesioneuroblastoma was responsible for increased FDG uptake. The combination of FDG PET and 111In-pentetreotide scintigraphy was useful for the pathophysiological evaluation of ACTH-secreting esthesioneuroblastoma.

AB - A 53-year-old woman with metastatic esthesioneuroblastoma was referred for FDG PET/CT imaging. FDG PET/CT showed symmetrical uptake in bilaterally enlarged adrenal glands, in addition to abnormal uptake in bone and lymph node metastases. 111In-pentetreotide scintigraphy was further performed and revealed the lack of adrenal uptake. The patient's serum adrenocorticotropic hormone (ACTH) level was extremely high, suggesting that hyperplastic condition in the adrenal glands due to ACTH stimulation from the metastatic esthesioneuroblastoma was responsible for increased FDG uptake. The combination of FDG PET and 111In-pentetreotide scintigraphy was useful for the pathophysiological evaluation of ACTH-secreting esthesioneuroblastoma.

KW - ACTH-secreting esthesioneuroblastoma

KW - FDG PET

KW - In pentetreotide scintigraphy

KW - adrenal hyperplasia

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Bilateral Adrenal Hyperplasia Due to Adrenocorticotropic Hormone-Secreting Esthesioneuroblastoma on FDG PET and 111In-Pentetreotide Scintigraphy

Abstract

Keywords

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