Bilateral multiple malignant transformation of Ollier's disease

N. Kosaki, H. Yabe, U. Anazawa, H. Morioka, M. Mukai, Y. Toyama

Research output: Contribution to journalArticlepeer-review

11 Citations (Scopus)


We treated a 26-year-old man with a 19-year history of Ollier's disease. Secondary chondrosarcomas developed metachronously at four separate locations: both femora, left proximal tibia and fibular head. All four lesions were surgically excised, and each specimen was histologically identified as grade 1 or 2 chondrosarcoma. Clinical follow-up for 20 years beginning at the time of first tumor surgery has shown no evidence of local recurrence or metastasis. This is the first report of multiple bilateral metachronous malignant transformation of multiple chondromatoses in a patient with Ollier's disease.

Original languageEnglish
Pages (from-to)477-484
Number of pages8
JournalSkeletal Radiology
Issue number8
Publication statusPublished - 2005 Aug
Externally publishedYes


  • Appendicular skeleton
  • MRI
  • Metachronous chondrosarcomas
  • Ollier's disease
  • Radiographs

ASJC Scopus subject areas

  • Radiology Nuclear Medicine and imaging


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