@inproceedings{8513212f1e2b4596b3c42960438cf56e,
title = "Biofabrication of living vessel structures integrated with fluid perfusion",
abstract = "This paper describes a biofabrication method of vessel-like structure with our gel fiber technology. Alginate was modified with gelatin to promote cell adhesion and proliferation, and treated with fibronectin (FN). Vascular endothelial cells (ECs) adhered and proliferated well on the modified alginate fiber. After embedding EC-coated fiber into extracellular matrix (ECM), ECs were transferred to ECM from the fiber, and then the fiber was easily removed with alginate lyase. Fluoresceinlabeled materials were flushed into the lumen, and it was observed small-sized molecules were leaked out to ECM. This approach would be applicable for the rapid biofabrication of functional luminal tissues.",
keywords = "Endothelial cell, Hydrogel fiber, Tissue engineering, Vessel structure",
author = "Shintaroh Iwanaga and Shigenori Miura and Hiroaki Onoe and Teru Okitsu and Shoji Takeuchi",
year = "2012",
month = jan,
day = "1",
language = "English",
isbn = "9780979806452",
series = "Proceedings of the 16th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2012",
publisher = "Chemical and Biological Microsystems Society",
pages = "1723--1725",
booktitle = "Proceedings of the 16th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2012",
note = "16th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2012 ; Conference date: 28-10-2012 Through 01-11-2012",
}