TY - GEN
T1 - Biological in vitro evaluations of three-dimensional scaffold developed from single-crystal apatite fibers for tissue engineering of bone
AU - Aizawa, M.
AU - Shinoda, H.
AU - Uchida, H.
AU - Okada, I.
AU - Fujimi, T. J.
AU - Kanzawa, N.
AU - Morisue, H.
AU - Matsumoto, M.
AU - Toyama, Y.
PY - 2004
Y1 - 2004
N2 - The biological properties of using two kinds of cells, MC3t3-E1 of an osteoblastic cell line and the rat bone-marrow cell (RBMC) as mesenchymal stem cell model were discussed. The HAp fiber was synthesized via a homogeneous precipitation method using urea. The HAp fiber was mixed with the spherical carbon beads having a diameter of ∼ 150 μm in the mixed solvent. The single HAp phase was present in the S0, S1000, and S2000 scaffolds with porosity of 95% over. The results show that the high porosity and large pore size fulfilled by S2000 could provide an excellent environment for enhancing bone marrow cell activity.
AB - The biological properties of using two kinds of cells, MC3t3-E1 of an osteoblastic cell line and the rat bone-marrow cell (RBMC) as mesenchymal stem cell model were discussed. The HAp fiber was synthesized via a homogeneous precipitation method using urea. The HAp fiber was mixed with the spherical carbon beads having a diameter of ∼ 150 μm in the mixed solvent. The single HAp phase was present in the S0, S1000, and S2000 scaffolds with porosity of 95% over. The results show that the high porosity and large pore size fulfilled by S2000 could provide an excellent environment for enhancing bone marrow cell activity.
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M3 - Conference contribution
AN - SCOPUS:13844321664
SN - 1877040193
T3 - Transactions - 7th World Biomaterials Congress
SP - 1568
BT - Transactions - 7th World Biomaterials Congress
T2 - Transactions - 7th World Biomaterials Congress
Y2 - 17 May 2004 through 21 May 2004
ER -