Biomarkers as a treatment guide in rheumatoid arthritis

Tsutomu Takeuchi

Research output: Contribution to journalArticlepeer-review

28 Citations (Scopus)


It is anticipated that biomarkers support rheumatologists to judge a group of patients that can improve the diagnosis and prognosis, and further facilitate appropriate and precise treatment with targeted therapy. In particular, biomarkers for predicting and monitoring response to biological disease modifying anti-rheumatic drugs (DMARDs) are demanding. Given the mechanism action of biological DMARDs is much more simple than the conventional synthetic DMARDs, a variety of approaches to find such biomarkers has been taken recent years. In this article, I will summarize the background for biomarker research and introduce recent topics in the research and the possible clinical applications of biomarkers to guide treatment in rheumatoid arthritis (RA).

Original languageEnglish
JournalClinical Immunology
Publication statusAccepted/In press - 2017


  • Biological agents
  • Biologics
  • Cytokine
  • Drug level
  • Treatment

ASJC Scopus subject areas

  • Immunology and Allergy
  • Immunology


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