Bioprosthetic tricuspid valve replacement in carcinoid heart disease from primary ovarian carcinoid tumor

Toshimitsu Tsugu, Shiro Iwanaga, Mitsushige Murata, Keiichi Fukuda

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4 Citations (Scopus)


Carcinoid heart disease (CHD) commonly occurs in association with primary gastrointestinal tract carcinoid tumors with hepatic metastases. Unlike primary gastrointestinal tract carcinoid tumors, primary ovarian carcinoid tumors may cause CHD without hepatic metastases, accounting for only 0.3 % of all carcinoid tumors. Only 37 cases of CHD from primary ovarian carcinoid tumors have been reported. We present a case of CHD in which tricuspid valve thickening and shortening led to reduced valve mobility with the resulting severe tricuspid regurgitation. Considering these characteristics of an abnormal tricuspid valve, we suspected CHD, but prosthetic valve replacement was performed without sufficient systemic examination before surgery. Two years after valve replacement, the patient underwent excision of a mass in the lower abdomen, which was diagnosed as an ovarian carcinoid tumor by histopathological examination. The patient has been observed for more than 3 years after tricuspid valve replacement. She has not experienced bioprosthetic valve leaflet degeneration or dysfunction, although it has been reported that bioprosthetic valves may degenerate in patients with carcinoid tumors. Sufficient systemic examinations should be performed to explore the cause of disease.

Original languageEnglish
Pages (from-to)401-403
Number of pages3
JournalJournal of Medical Ultrasonics
Issue number3
Publication statusPublished - 2015 Jul 21


  • Bioprosthetic valve replacement
  • Carcinoid heart disease
  • Cartinoid tumor
  • Echocardiography

ASJC Scopus subject areas

  • Radiology Nuclear Medicine and imaging


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