Biosynthesis of phytoecdysteroids in Ajuga hairy roots: Clerosterol as a precursor of cyasterone, isocyasterone and 29-norcyasterone

Keiko Okuzumi; Noriyuki Hara; Yoshinori Fujimoto; Junko Yamada; Atsuko Nakamura; Kyoko Takahashi; Masuo Morisaki

doi:10.1016/S0040-4039(02)02565-0

Biosynthesis of phytoecdysteroids in Ajuga hairy roots: Clerosterol as a precursor of cyasterone, isocyasterone and 29-norcyasterone

Keiko Okuzumi, Noriyuki Hara, Yoshinori Fujimoto, Junko Yamada, Atsuko Nakamura, Kyoko Takahashi, Masuo Morisaki

School of Pharmaceutical Sciences

Research output: Contribution to journal › Article › peer-review

14 Citations (Scopus)

Abstract

Feeding studies of six ¹³C-labeled sterols, including clerosterol, to hairy roots of Ajuga reptans var. atropurpurea have established that clerosterol is a precursor of three phytoecdysteroids, cyasterone, isocyasterone and 29-norcyasterone.

Original language	English
Pages (from-to)	323-326
Number of pages	4
Journal	Tetrahedron Letters
Volume	44
Issue number	2
DOIs	https://doi.org/10.1016/S0040-4039(02)02565-0
Publication status	Published - 2003 Jan 6

Keywords

29-norcyasterone
Biosynthesis
Clerosterol
Codisterol
Cyasterone
Ecdysteroids
Isocyasterone
Steroids and sterols

ASJC Scopus subject areas

Biochemistry
Drug Discovery
Organic Chemistry

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10.1016/S0040-4039(02)02565-0

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title = "Biosynthesis of phytoecdysteroids in Ajuga hairy roots: Clerosterol as a precursor of cyasterone, isocyasterone and 29-norcyasterone",

abstract = "Feeding studies of six 13C-labeled sterols, including clerosterol, to hairy roots of Ajuga reptans var. atropurpurea have established that clerosterol is a precursor of three phytoecdysteroids, cyasterone, isocyasterone and 29-norcyasterone.",

keywords = "29-norcyasterone, Biosynthesis, Clerosterol, Codisterol, Cyasterone, Ecdysteroids, Isocyasterone, Steroids and sterols",

author = "Keiko Okuzumi and Noriyuki Hara and Yoshinori Fujimoto and Junko Yamada and Atsuko Nakamura and Kyoko Takahashi and Masuo Morisaki",

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doi = "10.1016/S0040-4039(02)02565-0",

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T1 - Biosynthesis of phytoecdysteroids in Ajuga hairy roots

T2 - Clerosterol as a precursor of cyasterone, isocyasterone and 29-norcyasterone

AU - Okuzumi, Keiko

AU - Hara, Noriyuki

AU - Fujimoto, Yoshinori

AU - Yamada, Junko

AU - Nakamura, Atsuko

AU - Takahashi, Kyoko

AU - Morisaki, Masuo

PY - 2003/1/6

Y1 - 2003/1/6

N2 - Feeding studies of six 13C-labeled sterols, including clerosterol, to hairy roots of Ajuga reptans var. atropurpurea have established that clerosterol is a precursor of three phytoecdysteroids, cyasterone, isocyasterone and 29-norcyasterone.

AB - Feeding studies of six 13C-labeled sterols, including clerosterol, to hairy roots of Ajuga reptans var. atropurpurea have established that clerosterol is a precursor of three phytoecdysteroids, cyasterone, isocyasterone and 29-norcyasterone.

KW - 29-norcyasterone

KW - Biosynthesis

KW - Clerosterol

KW - Codisterol

KW - Cyasterone

KW - Ecdysteroids

KW - Isocyasterone

KW - Steroids and sterols

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ER -

Biosynthesis of phytoecdysteroids in Ajuga hairy roots: Clerosterol as a precursor of cyasterone, isocyasterone and 29-norcyasterone

Abstract

Keywords

ASJC Scopus subject areas

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