TY - JOUR
T1 - Biselides A-E
T2 - Novel polyketides from the Okinawan ascidian Didemnidae sp.
AU - Teruya, Toshiaki
AU - Suenaga, Kiyotake
AU - Maruyama, Sakiko
AU - Kurotaki, Mineko
AU - Kigoshi, Hideo
N1 - Funding Information:
We would like to thank Professor T. Nishikawa (Nagoya University) for identifying the ascidian and Professor D. Uemura (Nagoya University) for helpful information of bioactivities of haterumalides. This work was supported in part by the 21st COE program from the Ministry of Education, Culture, Sports, Science, and Technology, Japan, University of Tsukuba Projects, Suntory Institute for Bioorganic Research, and Kurita Water and Environment Foundation.
PY - 2005/7/4
Y1 - 2005/7/4
N2 - Five new polyketides, biselides A (1), B (2), C (3), D (4), and E (5), were isolated from the Okinawan ascidian Didemnidae sp. Their structures were determined by spectroscopic analysis. Biselides A (1), B (2), and C (3) showed cytotoxicity against human cancer cells NCI-H460 and MDA-MB-231.
AB - Five new polyketides, biselides A (1), B (2), C (3), D (4), and E (5), were isolated from the Okinawan ascidian Didemnidae sp. Their structures were determined by spectroscopic analysis. Biselides A (1), B (2), and C (3) showed cytotoxicity against human cancer cells NCI-H460 and MDA-MB-231.
KW - Ascidian
KW - Cytotoxicity
KW - Macrolide
KW - Marine natural product
KW - Polyketide
UR - http://www.scopus.com/inward/record.url?scp=20444502594&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=20444502594&partnerID=8YFLogxK
U2 - 10.1016/j.tet.2005.04.052
DO - 10.1016/j.tet.2005.04.052
M3 - Article
AN - SCOPUS:20444502594
SN - 0040-4020
VL - 61
SP - 6561
EP - 6567
JO - Tetrahedron
JF - Tetrahedron
IS - 27
ER -
