Bladder tumor staging: Comparison of conventional and gadolinium-enhanced dynamic MR imaging and CT

Akihiro Tanimoto, Yuji Yuasa, Yutaka Imai, Mutsumi Izutsu, Kyoichi Hiramatsu, Masaaki Tachibana, Hiroshi Tazaki

Research output: Contribution to journalReview articlepeer-review

92 Citations (Scopus)


With computed tomography (CT) and unenhanced magnetic resonance (MR) imaging, stage pT3b extravesical extension and beyond can be diagnosed, but tumors confined to the bladder wall (stages pT1-pT3a) are poorly delineated. To determine whether visualization of such tumors could be improved with gadoliniumenhanced MR imaging, dynamic breath-hold T1-weighted MR images were obtained after intravenous infusion of 0.1 mmol/kg gadopentetate dimeglumine in 79 patients (86 tumors). Conventional MR images, CT scans, and histologic correlation were available in all cases. With dynamic gadolinium-enhanced MR imaging, the mucosa could be distinguished from the muscular layers of the bladder wall. Staging accuracy with this technique was 85% (73 of 86), which was significantly better than with CT (55%; 47 of 86) (P < .005) or conventional MR imaging (58%; 50 of 86) (P < .05). The accuracy of staging the intramural extent (pT1-pT3a) of bladder tumors was thus improved with gadolinium-enhanced dynamic MR imaging.

Original languageEnglish
Pages (from-to)741-747
Number of pages7
Issue number3
Publication statusPublished - 1992 Dec


  • Bladder neoplasms, CT, 83.1211, 83.321
  • Bladder neoplasms, MR, 83.1214
  • Bladder neoplasms, staging, 83.321
  • Gadolinium
  • Magnetic resonance (MR), comparative studies, 83.1211, 83.1214
  • Magnetic resonance (MR), contrast enhancement

ASJC Scopus subject areas

  • Radiology Nuclear Medicine and imaging


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