Burow's solution-induced acute sensorineural hearing loss: Report of two cases

Naoki Oishi, Yasuhiro Inoue, Hideyuki Saito, Kaoru Ogawa

Research output: Contribution to journalArticlepeer-review

8 Citations (Scopus)


This is the report of rare cases to show the potential ototoxicity of Burow's solution in clinical use. We encountered two cases of acute sensorineural hearing loss occurring after the administration of 8% Burow's solution (pH 2.93) into the tympanic cavities. Prior to treatment, both cases presented with tympanic membrane perforations in the posterior and inferior portions and a small amount of serous discharge. Fortunately, hearing loss recovered almost completely except for high tones within a few weeks. These two case reports demonstrate that the ototoxicity of Burow's solution should be considered when it is used to treat otitis media accompanied by tympanic membrane perforation.

Original languageEnglish
Pages (from-to)369-372
Number of pages4
JournalAuris Nasus Larynx
Issue number3
Publication statusPublished - 2010 Jun 1


  • Acidity
  • Burow's solution
  • Ototoxicity
  • Round window membrane
  • Sensorineural hearing loss

ASJC Scopus subject areas

  • Surgery
  • Otorhinolaryngology


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