Catalytic asymmetric syntheses of syn aldols with a methyl ketone functionality were studied to confirm the generality of the methodology. In addition, catalytic asymmetric synthesis of anti aldols with a thioamide group was carefully examined, giving the desired products, albeit with moderate diastereoselectivity.
- aldol reaction
- catalytic asymmetric reaction
- methyl A-Ketone
ASJC Scopus subject areas
- Organic Chemistry