Catalytic Conjugate Additions of Alkynes

Naoya Kumagai, Masakatsu Shibasaki

Research output: Chapter in Book/Report/Conference proceedingChapter

1 Citation (Scopus)


Recent advances in conjugate addition of alkynes are summarized. Since the initial developments using metalated alkynes, the focus of this field has shifted to the direct use of terminal alkynes through advanced catalytic systems. Several examples of enantioselective catalysis have allowed us to produce synthetically versatile enantioenriched β-alkynyl carbonyl compounds.

Original languageEnglish
Title of host publicationModern Alkyne Chemistry
Subtitle of host publicationCatalytic and Atom-Economic Transformations
PublisherWiley Blackwell
Number of pages30
ISBN (Electronic)9783527677894
ISBN (Print)9783527335053
Publication statusPublished - 2015 Feb 9
Externally publishedYes


  • Metal alkynylide
  • Terminal alkyne
  • α,β-unsaturated compounds
  • β-alkynyl carbonyl compounds

ASJC Scopus subject areas

  • Chemistry(all)


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