Abstract
In the presence of a catalytic amount of the optically active β-ketoiminato cobalt(II) complex and borohydride modified with appropriate alcohols, the 1,4-reduction of α-substituted-α,β-unsaturated carboxamides followed by in situ enantioselective protonation proceeded smoothly to afford optically active α-substituted carboxamides with good enantiomeric excess.
Original language | English |
---|---|
Pages (from-to) | 967-970 |
Number of pages | 4 |
Journal | Tetrahedron Asymmetry |
Volume | 14 |
Issue number | 8 |
DOIs | |
Publication status | Published - 2003 Apr 18 |
ASJC Scopus subject areas
- Catalysis
- Physical and Theoretical Chemistry
- Organic Chemistry
- Inorganic Chemistry