Centrifuge-based dynamic microarray system toward an array of a few amount of sample

H. Hasegawa; T. Teshima; H. Onoe; S. Takeuchi

doi:10.1109/MEMSYS.2013.6474467

Centrifuge-based dynamic microarray system toward an array of a few amount of sample

H. Hasegawa, T. Teshima, H. Onoe, S. Takeuchi

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution

Abstract

In this study, we purpose a centrifuge-based dynamic microarray system (CDM) for trapping micro-sized samples sequentially from only 10 μl of the samples. Our system enables us to make an array of microbeads only with a spin-coater. The air can be introduced to the microchannel to isolate and encapsulate the trapped beads by the specific speed rotation because the microbeads were fixed at the outlet of the trapping spots by the centrifugal force. We optimized rotation speed for trapping with the high trapping yield and successfully controlled sample/solution/air introduction. This device can also release the trapped beads by flowing liquid backward, which allows us to retrieve the microbeads and reuse the device. The presented technology marks an essential step towards a high efficient portable CDM for point-of-care use.

Original language	English
Title of host publication	IEEE 26th International Conference on Micro Electro Mechanical Systems, MEMS 2013
Pages	1199-1202
Number of pages	4
DOIs	https://doi.org/10.1109/MEMSYS.2013.6474467
Publication status	Published - 2013 Apr 2
Externally published	Yes
Event	IEEE 26th International Conference on Micro Electro Mechanical Systems, MEMS 2013 - Taipei, Taiwan, Province of China Duration: 2013 Jan 20 → 2013 Jan 24

Publication series

Name	Proceedings of the IEEE International Conference on Micro Electro Mechanical Systems (MEMS)
ISSN (Print)	1084-6999

Other

Other	IEEE 26th International Conference on Micro Electro Mechanical Systems, MEMS 2013
Country/Territory	Taiwan, Province of China
City	Taipei
Period	13/1/20 → 13/1/24

ASJC Scopus subject areas

Electronic, Optical and Magnetic Materials
Condensed Matter Physics
Mechanical Engineering
Electrical and Electronic Engineering

Access to Document

10.1109/MEMSYS.2013.6474467

Cite this

Hasegawa, H., Teshima, T., Onoe, H., & Takeuchi, S. (2013). Centrifuge-based dynamic microarray system toward an array of a few amount of sample. In IEEE 26th International Conference on Micro Electro Mechanical Systems, MEMS 2013 (pp. 1199-1202). Article 6474467 (Proceedings of the IEEE International Conference on Micro Electro Mechanical Systems (MEMS)). https://doi.org/10.1109/MEMSYS.2013.6474467

Centrifuge-based dynamic microarray system toward an array of a few amount of sample. / Hasegawa, H.; Teshima, T.; Onoe, H. et al.
IEEE 26th International Conference on Micro Electro Mechanical Systems, MEMS 2013. 2013. p. 1199-1202 6474467 (Proceedings of the IEEE International Conference on Micro Electro Mechanical Systems (MEMS)).

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution

Hasegawa, H, Teshima, T, Onoe, H & Takeuchi, S 2013, Centrifuge-based dynamic microarray system toward an array of a few amount of sample. in IEEE 26th International Conference on Micro Electro Mechanical Systems, MEMS 2013., 6474467, Proceedings of the IEEE International Conference on Micro Electro Mechanical Systems (MEMS), pp. 1199-1202, IEEE 26th International Conference on Micro Electro Mechanical Systems, MEMS 2013, Taipei, Taiwan, Province of China, 13/1/20. https://doi.org/10.1109/MEMSYS.2013.6474467

Hasegawa H, Teshima T, Onoe H, Takeuchi S. Centrifuge-based dynamic microarray system toward an array of a few amount of sample. In IEEE 26th International Conference on Micro Electro Mechanical Systems, MEMS 2013. 2013. p. 1199-1202. 6474467. (Proceedings of the IEEE International Conference on Micro Electro Mechanical Systems (MEMS)). doi: 10.1109/MEMSYS.2013.6474467

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abstract = "In this study, we purpose a centrifuge-based dynamic microarray system (CDM) for trapping micro-sized samples sequentially from only 10 μl of the samples. Our system enables us to make an array of microbeads only with a spin-coater. The air can be introduced to the microchannel to isolate and encapsulate the trapped beads by the specific speed rotation because the microbeads were fixed at the outlet of the trapping spots by the centrifugal force. We optimized rotation speed for trapping with the high trapping yield and successfully controlled sample/solution/air introduction. This device can also release the trapped beads by flowing liquid backward, which allows us to retrieve the microbeads and reuse the device. The presented technology marks an essential step towards a high efficient portable CDM for point-of-care use.",

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Centrifuge-based dynamic microarray system toward an array of a few amount of sample

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