TY - JOUR
T1 - Changes in Muscle Shear Modulus and Urinary Titin N-Terminal Fragment after Eccentric Exercise
AU - Inami, Takayuki
AU - Yamaguchi, Shota
AU - Ishida, Hiroyuki
AU - Kohtake, Naohiko
AU - Morito, Akihisa
AU - Yamada, Satoshi
AU - Shimomasuda, Masatsugu
AU - Haramoto, Maki
AU - Nagata, Naoya
AU - Murayama, Mitsuyoshi
N1 - Funding Information:
Taisho Pharmaceutical Co., Ltd. funded and collaborated with this study; however, the company did not influence the scientific interpretation of the collected data or the publication of this article. The authors declare that this study complies with the laws and regulations of the host country.
Publisher Copyright:
© 2022, Journal of Sport Science and Medicine. All rights reserved.
PY - 2022/12
Y1 - 2022/12
N2 - This study aimed to investigate the relationship between the muscle shear modulus of the biceps brachii, urinary titin N-terminal fragment (UTF), and other damage markers after eccentric exer-cise. Seventeen healthy males performed five sets of ten eccentric exercises with dumbbells weighing 50% of the maximum voluntary contraction (MVC) at the elbow joint. Muscle shear modulus with range of interest set to only biceps brachii muscle measured by ultrasound shear wave elastography, UTF, MVC, range of motion (ROM), and soreness (SOR) were recorded before, immedi-ately after, and 1, 24, 48, 72, 96, and 168 h after eccentric exer-cise. Each marker changed in a time course pattern, as found in previous studies. The peak shear modulus showed a moderate negative correlation with peak MVC (r = –0.531, P < 0.05) and a strong positive correlation with peak UTF (r = 0.707, P < 0.01). Our study results revealed a significant relationship between muscle strength, shear modulus measured by ultrasound SWE, and titin measured by UTF, as a non-invasive damage marker after eccentric exercise to track changes in EIMD.
AB - This study aimed to investigate the relationship between the muscle shear modulus of the biceps brachii, urinary titin N-terminal fragment (UTF), and other damage markers after eccentric exer-cise. Seventeen healthy males performed five sets of ten eccentric exercises with dumbbells weighing 50% of the maximum voluntary contraction (MVC) at the elbow joint. Muscle shear modulus with range of interest set to only biceps brachii muscle measured by ultrasound shear wave elastography, UTF, MVC, range of motion (ROM), and soreness (SOR) were recorded before, immedi-ately after, and 1, 24, 48, 72, 96, and 168 h after eccentric exer-cise. Each marker changed in a time course pattern, as found in previous studies. The peak shear modulus showed a moderate negative correlation with peak MVC (r = –0.531, P < 0.05) and a strong positive correlation with peak UTF (r = 0.707, P < 0.01). Our study results revealed a significant relationship between muscle strength, shear modulus measured by ultrasound SWE, and titin measured by UTF, as a non-invasive damage marker after eccentric exercise to track changes in EIMD.
KW - Shear wave elastography
KW - exercise-induced muscle damage
KW - non-invasive method
KW - sarcomere
KW - stiffness
UR - http://www.scopus.com/inward/record.url?scp=85143802535&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=85143802535&partnerID=8YFLogxK
U2 - 10.52082/jssm.2022.536
DO - 10.52082/jssm.2022.536
M3 - Article
C2 - 36523897
AN - SCOPUS:85143802535
SN - 1303-2968
VL - 21
SP - 536
EP - 544
JO - Journal of Sports Science and Medicine
JF - Journal of Sports Science and Medicine
IS - 4
ER -