Changes in quality of care and quality of life of outpatients with advanced cancer after a regional palliative care intervention program

Akemi Yamagishi, Kazuki Sato, Mitsunori Miyashita, Yasuo Shima, Yoshiyuki Kizawa, Megumi Umeda, Hiroya Kinoshita, Yutaka Shirahige, Miki Akiyama, Takuhiro Yamaguchi, Tatsuya Morita

Research output: Contribution to journalArticlepeer-review

12 Citations (Scopus)


Conclusion. Although average changes in patient-reported outcomes were relatively small in the total sample of patients, the intervention seemed to provide tangible benefits for the patients with poor general conditions. A future regional intervention trial should include patient outcomes in those with a poor general condition to evaluate the net effects of the program.

Context. A recent mixed-methods study to evaluate the effects of a comprehensive regional palliative care program, the Japan Outreach Palliative Care Trial of the Integrated Model study, achieved broad positive outcomes at a regional level. This is a secondary analysis of patient outcomes.

Objectives. The primary aims were to explore: 1) the changes in domains of patient-reported quality of care and quality of life after interventions, and 2) the changes in quality of care and quality of life of patients with different characteristics (i.e., performance status, age, and anticancer treatment).

Methods. A region-representative sample of metastatic/locally advanced cancer patients in outpatient settings participated in questionnaire surveys before and after regional intervention. Responses were obtained from 859 of 1880 and 857 of 2123 in the pre- and postintervention surveys, respectively.

Results. All subdomain scores of the quality of care, except for help with decision making, significantly improved in the postintervention survey. The percentages of the patients who reported that improvement was necessary decreased from 13% to 5.0%. Although there were no or only a marginally significant difference in total and subdomain scores of quality of life between preintervention and postintervention surveys, the subgroups of patients with a poor performance status and those receiving no anticancer treatment achieved a significant improvement in the quality of life.

Original languageEnglish
Pages (from-to)602-610
Number of pages9
JournalJournal of Pain and Symptom Management
Issue number4
Publication statusPublished - 2014 Oct 1


  • Palliative care
  • outpatient
  • patient
  • quality of care
  • quality of care
  • region

ASJC Scopus subject areas

  • General Nursing
  • Clinical Neurology
  • Anesthesiology and Pain Medicine


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